Evidence map›Paper›PMID 40295764›Full record

ArticleNature chemical biology2026

Monitoring in real time and far-red imaging of H

Justin Daho Lee, Amanda Nguyen, Chelsea E Gibbs, Zheyu Ruby Jin, Yuxuan Wang, Aida Moghadasi, Sarah J Wait, Hojun Choi, Kira M Evitts, Anthony Asencio and 14 more

Abstract read
In one paragraph

Article in Nature chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Justin Daho LeeMolecular Engineering and Sciences Institute, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0284-2389
Amanda NguyenDepartment of Bioengineering, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0009-0001-7104-8226
Chelsea E Gibbs *Department of Bioengineering, University of Washington, Seattle, WA, USA.
Zheyu Ruby Jin *Department of Chemical Engineering, University of Washington, Seattle, WA, USA.
Yuxuan Wang *Department of Bioengineering, University of Washington, Seattle, WA, USA.
Aida MoghadasiDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Sarah J WaitMolecular Engineering and Sciences Institute, University of Washington, Seattle, WA, USA.
Hojun ChoiDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Kira M EvittsDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Anthony AsencioDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Samantha B BremnerDepartment of Bioengineering, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-3465-0442
Shani ZunigaDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Vedant ChavanDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Inez K A PranotoInstitute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0709-5642
C Andrew WilliamsInstitute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Annette SmithInstitute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Farid Moussavi-HaramiInstitute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0189-7214
Michael RegnierDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
David BakerDepartment of Biochemistry, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-7896-6217
Jessica E YoungInstitute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
David L MackDepartment of Bioengineering, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-1340-7056
Elizabeth NanceMolecular Engineering and Sciences Institute, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-7167-7068
Patrick M BoyleDepartment of Bioengineering, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9048-1239
Andre BerndtMolecular Engineering and Sciences Institute, University of Washington, Seattle, WA, USA. berndtuw@uw.edu.ORCID http://orcid.org/0000-0003-4758-5598

Funding

University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Charles Chavkin · 2019 to 2026
$13.0M
From proteins to cells to tissues: A multi-scale assessment of biomechanical regulation by the myosin molecular motorRM1GM131981 · NIGMS · STANFORD UNIVERSITY · PI BERNSTEIN, DANIEL, MACK, DAVID LEE · 2019 to 2023
$10.3M
UW Center for Translational Muscle Research (Overall Application)P30AR074990 · NIAMS · UNIVERSITY OF WASHINGTON · PI Jennifer Michelle Davis · 2019 to 2026
$7.5M
Biological Mechanisms of Healthy Aging Training GrantT32AG066574 · NIA · UNIVERSITY OF WASHINGTON · PI David J. Marcinek, Jessica E Young · 2020 to 2026
$5.3M
Next Generation Opto-GPCRs for Neuromodulatory ControlU01NS128537 · NINDS · UNIVERSITY OF WASHINGTON · PI Andre Berndt, Michael R. Bruchas · 2023 to 2026
$4.4M
Experimental and Computational Studies in Genetic CardiomyopathiesR01HL157169 · NHLBI · UNIVERSITY OF WASHINGTON · PI Farid Moussavi-Harami · 2022 to 2026
$3.3M
High-throughput engineering of ligand-selective fluorescent biosensors for detecting endogenous and exogenous opioidsRF1MH130391 · NIMH · UNIVERSITY OF WASHINGTON · PI BERNDT, ANDRE, BRUCHAS, MICHAEL R. · 2023 to 2023
$2.5M
Structure-guided and high-throughput engineering of genetically encoded sensors for reactive oxygen speciesR01GM139850 · NIGMS · UNIVERSITY OF WASHINGTON · PI BERNDT, ANDRE · 2021 to 2024
$1.6M
Bioengineering Cardiovascular Training Grant (BCTG)T32EB032787 · NIBIB · UNIVERSITY OF WASHINGTON · PI MICHAEL REGNIER, Ying Zheng · 2022 to 2026
$969k
In vivo real-time monitoring of reactive oxygen species and opioid signaling in a model for opioid receptor activity.R21DA051193 · NIDA · UNIVERSITY OF WASHINGTON · PI BERNDT, ANDRE · 2021 to 2022
$461k
Deciphering biased agonistic activation of mu-opioid receptor by novel optogenetic hydrogen peroxide sensorF31DA056121 · NIDA · UNIVERSITY OF WASHINGTON · PI LEE, JUSTIN · 2022 to 2024
$85k
NHLBI NIH HHS R01 HL157169NIAMS NIH HHS P30 AR074990NIA NIH HHS T32 AG066574NIBIB NIH HHS T32 EB032787NIDA NIH HHS F31 DA056121NIDA NIH HHS P30 DA048736NIDA NIH HHS R21 DA051193NIGMS NIH HHS R01 GM139850NIGMS NIH HHS RM1 GM131981NIMH NIH HHS RF1 MH130391NINDS NIH HHS U01 NS128537
6 · The paper itself

Abstract

Monitoring H

Indexed as

Fluorescent DyesHydrogen PeroxideCalciumHumansOptogeneticsOxidation-ReductionCalciumFluorescent DyesHydrogen Peroxide

Identifiers

PMID40295764
PMCPMC12995517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.