Evidence map›Paper›PMID 40295704›Full record

ArticleNpj viruses2024

Inferring enterovirus D68 transmission dynamics from the genomic data of two 2022 North American outbreaks.

Martin Grunnill, Alireza Eshaghi, Lambodhar Damodaran, Sandeep Nagra, Ali Gharouni, Thomas Braukmann, Shawn Clark, Adriana Peci, Sandra Isabel, Philip Banh and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Npj viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Prevalence and epidemiology of enterovirus species in a pediatric oncology patient population.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Martin GrunnillPublic Health Ontario, Toronto, ON, Canada.
Alireza EshaghiPublic Health Ontario, Toronto, ON, Canada.
Lambodhar DamodaranDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Sandeep NagraPublic Health Ontario, Toronto, ON, Canada.
Ali GharouniPublic Health Ontario, Toronto, ON, Canada.
Thomas BraukmannPublic Health Ontario, Toronto, ON, Canada.
Shawn ClarkPublic Health Ontario, Toronto, ON, Canada.
Adriana PeciPublic Health Ontario, Toronto, ON, Canada.
Sandra IsabelPublic Health Ontario, Toronto, ON, Canada.
Philip BanhPublic Health Ontario, Toronto, ON, Canada.
Louis du PlessisDepartment of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.
Carmen Lia MurallNational Microbiology Laboratory, Public Health Agency of Canada, Montreal, QC, Canada.
Caroline ColijnDepartment of Mathematics, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada.
Samira MubarekaDepartment of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Maan HassoPublic Health Ontario, Toronto, ON, Canada.
Justin BahlCenter for the Ecology of Infectious Disease, Department of Infectious Diseases, Department of Epidemiology and Biostatistics, Institute of Bioinformatics, University of Georgia, Athens, GA, USA.
Heba H MostafaDivision of Medical Microbiology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Jonathan B GubbayPublic Health Ontario, Toronto, ON, Canada.
Samir N PatelPublic Health Ontario, Toronto, ON, Canada.
Jianhong WuLaboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, ON, Canada.
Venkata R DuvvuriPublic Health Ontario, Toronto, ON, Canada. Venkata.Duvvuri@oahpp.ca.ORCID http://orcid.org/0000-0001-7356-338X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus D68 (EV-D68) has emerged as a significant cause of acute respiratory illness in children globally, notably following its extensive outbreak in North America in 2014. A recent outbreak of EV-D68 was observed in Ontario, Canada, from August to October 2022. Our phylogenetic analysis revealed a notable genetic similarity between the Ontario outbreak and a concurrent outbreak in Maryland, USA. Utilizing Bayesian phylodynamic modeling on whole genome sequences (WGS) from both outbreaks, we determined the median peak time-varying reproduction number (R

Identifiers

PMID40295704
PMCPMC11721450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.