Evidence map›Paper›PMID 40295620›Full record

ArticleScientific reports2025

Enhanced alcohol metabolism and sleep quality with continuous positive airway pressure following alcohol consumption.

Hyun Jun Kim, Do-Yang Park, Wee Gyo Lee, Kang Il Lee, Jin Ji Jung, Han Sang Lee, Sang In Hwang, Ji Hyun Park, Bumhee Park

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hyun Jun KimSleep Center, Ajou University Hospital, 164 World cup-ro, Yeongtong-gu, Suwon-si, Gyonggi-do, 16499, Republic of Korea. entkhj@ajou.ac.kr.
Do-Yang ParkSleep Center, Ajou University Hospital, 164 World cup-ro, Yeongtong-gu, Suwon-si, Gyonggi-do, 16499, Republic of Korea.
Wee Gyo LeeDepartment of Laboratory Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.
Kang Il LeeSleep Center, Ajou University Hospital, 164 World cup-ro, Yeongtong-gu, Suwon-si, Gyonggi-do, 16499, Republic of Korea.
Jin Ji JungSleep Center, Ajou University Hospital, 164 World cup-ro, Yeongtong-gu, Suwon-si, Gyonggi-do, 16499, Republic of Korea.
Han Sang LeeSleep Center, Ajou University Hospital, 164 World cup-ro, Yeongtong-gu, Suwon-si, Gyonggi-do, 16499, Republic of Korea.
Sang In HwangSleep Center, Ajou University Hospital, 164 World cup-ro, Yeongtong-gu, Suwon-si, Gyonggi-do, 16499, Republic of Korea.
Ji Hyun ParkOffice of Biostatistics, Medical Research Collaborating Center, Ajou Research Institute for Innovative Medicine, Ajou University Medical Center, Suwon, Republic of Korea.
Bumhee ParkOffice of Biostatistics, Medical Research Collaborating Center, Ajou Research Institute for Innovative Medicine, Ajou University Medical Center, Suwon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to examine the effect of continuous positive airway pressure on sleep quality and alcohol metabolism after alcohol consumption. Men (n = 53) aged ≥ 19 years with sleep disorders who regularly consumed an average of ≥ 1.0 g of alcohol/kg of bodyweight, were free of serious diseases (including liver disorders), and underwent polysomnography and continuous positive airway pressure titration between January 2016 and July 2021 were included. Participants drank a high dose of a traditional Korean liquor at a rate of 1.0 g/kg of bodyweight for 1 h. The main outcome measures included polysomnography results and blood and breath ethanol and acetaldehyde concentrations after alcohol consumption before and after sleep. Statistical analyses were performed using R software, version 4.0.5 (R Foundation, Vienna, Austria). Continuous positive airway pressure enhanced sleep quality after alcohol consumption, with oxygen significantly improving the metabolism of acetaldehyde over that of ethanol. Breath and blood sample analyses and polysomnography results revealed that continuous positive airway pressure improved sleep quality by reducing apnea-hypopnea index by 27.32 ± 24.87 (p < 0.001), increasing rapid eye movement sleep by 2.08 ± 6.74% (p < 0.05), and enhancing acetaldehyde breakdown by 21.2% (p < 0.001), while its effect on ethanol breakdown (4-5%) was not statistically significant. Continuous positive airway pressure is recommended after alcohol consumption for individuals with sleep apnea to enhance sleep quality.

Indexed as

Alcohol DrinkingContinuous Positive Airway PressureEthanolSleep QualityAcetaldehydeAdultHumansMaleMiddle AgedPolysomnographyAcetaldehydeEthanolAcetaldehydeEthanolHypoxiaOxygen

Identifiers

PMID40295620
PMCPMC12037736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.