Evidence map›Paper›PMID 40295569›Full record

ArticleScientific reports2025

The role of pH on structure, corrosion behavior and biocompatibility of MgFe layered double hydroxide coating on Mg-Nd-Zn-Zr alloy.

Rui Yue, Ruotong Zhu, Suqin Wang, Lingyu Li, Yusheng Zuo, Jianzhao Chen, Shaoding Sheng

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rui YueSchool of Materials Science and Engineering, Anhui University of Science and Technology, Huai Nan, 232001, China. yuerui5275@163.com.
Ruotong ZhuSchool of Materials Science and Engineering, Anhui University of Science and Technology, Huai Nan, 232001, China.
Suqin WangSchool of Materials Science and Engineering, Anhui University of Science and Technology, Huai Nan, 232001, China.
Lingyu LiShandong Key Laboratory for Magnetic Field-Free Medicine & Functional Imaging, Institute of Magnetic Field-free Medicine &·Functional Imaging, Jinan, 250012, China. lilingyu10487@qiluhospital.com.
Yusheng ZuoSchool of Materials Science and Engineering, Anhui University of Science and Technology, Huai Nan, 232001, China.
Jianzhao ChenSchool of Materials Science and Engineering, Anhui University of Science and Technology, Huai Nan, 232001, China.
Shaoding ShengSchool of Materials Science and Engineering, Anhui University of Science and Technology, Huai Nan, 232001, China.

Funding

Anhui Science and Technology Environmental Friendly Materials and Occupational Health Research Institute Industry-University-Research Project ALW2022YF01Anhui university students innovation and entrepreneurship training program S202410361036Scientific Research Foundation for High-level Talents of Anhui University of Science and Technology 13210573the University Natural Science Foundation of Anhui Province 2022AH050799
6 · The paper itself

Abstract

In the present study, MgFe layered double hydroxide (LDHs) coatings were prepared on the surface of Mg-Nd-Zn-Zr (JDBM) alloy by a chemical conversion method, and the effects of the pH value (pH = 8, 10 and 12) of the prepared solution on the morphology, corrosion resistance and biocompatibility of the coatings were studied. The thickness of the Mg-Fe LDHs coatings was 43.79 ± 3.65 μm (pH = 8), 46.18 ± 1.05 μm (pH = 10) and 28.71 ± 4.05 μm (pH = 12), respectively. The corrosion rate of the JDBM matrix in simulated body fluid was 3.1 ± 0.1 mm/year, the LDHs coating significantly slowed down the corrosion process. When the pH of the mixed solution was 10, the Mg-Fe LDHs coatings exhibited the lowest corrosion rate (0.07 ± 0.008 mm/year). The cell experiment results indicate the Mg-Fe LDHs coating significantly enhances the cell viability of both EA.hy926 cells and A7r5 cells. At a 50% extract concentration, the cell viability for the JDBM alloy was 70% (EA.hy926) and 61% (A7r5), respectively, while the cell viability for the Mg-Fe LDHs coatings exceeded 95% for both EA.hy926 cells and A7r5 cells. In addition, the hemolysis ratio of the coated sample is about 1.7%, much lower than that of the JDBM alloy (46.7%), meeting the clinical requirements for medical materials with a hemolysis ratio below 5%. Based on the above results, the corrosion resistance and in vitro biocompatibilities of the JDBM alloy are significantly improved by the Mg-Fe LDHs coatings.

Indexed as

AlloysCoated Materials, BiocompatibleHydroxidesCell LineCell SurvivalCorrosionHumansHydrogen-Ion ConcentrationIronMagnesiumMaterials TestingSurface PropertiesAlloysCoated Materials, BiocompatibleHydroxidesIronMagnesiumMg-Nd-Zn-Zr alloyBiocompatibilityCorrosion behaviorLDHs coatingsMg–Nd–Zn–Zr alloypH value

Identifiers

PMID40295569
PMCPMC12037841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.