Evidence map›Paper›PMID 40295555›Full record

ArticleNature communications2025

White light-excited organic room-temperature phosphorescence for improved in vivo bioimaging.

Lutong Zhang, Jisen Li, Yifan Zhang, Wenbo Dai, Yufan Zhang, Xue Gao, Miaochang Liu, Huayue Wu, Xiaobo Huang, Yunxiang Lei and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Organic Afterglow Vesicles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lutong Zhang *School of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China.
Jisen Li *Frontiers Science Center for New Organic Matter, State Key Laboratory of Medicinal Chemical Biology, MOE Key Laboratory of Bioactive Materials, and College of Life Sciences, Nankai University, Tianjin, P.R. China.
Yifan ZhangSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China.
Wenbo DaiSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China. wbdai@wzu.edu.cn.ORCID http://orcid.org/0009-0004-1382-3038
Yufan ZhangFrontiers Science Center for New Organic Matter, State Key Laboratory of Medicinal Chemical Biology, MOE Key Laboratory of Bioactive Materials, and College of Life Sciences, Nankai University, Tianjin, P.R. China.
Xue GaoSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China.
Miaochang LiuSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China.
Huayue WuSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China.
Xiaobo HuangSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China.ORCID http://orcid.org/0000-0002-4876-8372
Yunxiang LeiSchool of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, P. R. China. yunxianglei@wzu.edu.cn.ORCID http://orcid.org/0000-0002-3300-0811
Dan DingFrontiers Science Center for New Organic Matter, State Key Laboratory of Medicinal Chemical Biology, MOE Key Laboratory of Bioactive Materials, and College of Life Sciences, Nankai University, Tianjin, P.R. China. dingd@nankai.edu.cn.ORCID http://orcid.org/0000-0003-1873-6510

Funding

National Natural Science Foundation of China (National Science Foundation of China) U21A2097
6 · The paper itself

Abstract

Organic phosphorescence materials offer significant advantages for bioimaging applications. However, most of these materials are excited exclusively by ultraviolet (UV) light, which poses risks to living organisms. Herein, six donor-acceptor-type compounds incorporating triazine groups are designed as guests within doped systems. White-light excitable phosphorescent guests enable doped materials to show efficient afterglow under white-light excitation. By leveraging the ability of white-light to penetrate biological tissues, a bioimaging mode in which the materials are first concentrated within the organism and then excited was developed, yielding superior imaging effects compared with the traditional method in which materials are first excited and then concentrated. Furthermore, these materials are applied in imaging diagnosis of atherosclerosis plaques (male Apoe

Indexed as

Luminescent AgentsOptical ImagingAnimalsFemaleHumansLightLiver NeoplasmsLuminescent MeasurementsMaleMiceMice, Inbred BALB CMice, NudePlaque, AtheroscleroticTemperatureTriazinesUltraviolet RaysLuminescent AgentsTriazines

Identifiers

PMID40295555
PMCPMC12037864

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.