ReviewCurrent microbiology2025
Unraveling the Nano World in Paracoccidioidomycosis: Promising Applications of Nanotechnology in Diagnosis, Treatment, and Vaccines: A Mini Review.
Review in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paracoccidioidomycosis (PCM) is a systemic mycosis caused by fungi of the genus Paracoccidioides. This disease is prevalent in Latin America, with Brazil being an endemic region. This mycosis can be classified as PCM infection, PCM disease and residual PCM. Although diagnosis and treatment exist, they have some limitations, and there is no vaccine available for this disease. Thus, the application of nanotechnology in the biomedical and health areas has become an innovative alternative. In this review, we highlight the main advances in the use of nanotechnology to improve and/or develop methods of diagnosis, treatment and vaccines for PCM. In order to improve diagnostic methods, nanoparticles can be used as biosensors associated with cell biology and spectroscopy techniques. The use of nanomaterials of different shapes and nature can act directly on the pathogen or as drug carriers, maintaining or improving antifungal activity and reducing toxicity in vitro and in vivo. In addition, nanoparticulate systems could be an important tool for vaccine development, stimulating a Th1 response, which is considered protective in PCM.
Indexed as
Identifiers
40295332What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.