Evidence map›Paper›PMID 40295327›Full record

ArticleCurrent microbiology2025

Impact of Periodontal Disease on the Oral Microbiome of Cats.

Pamela Thomson, Rodrigo Santibáñez, Daniel Garrido, María Paz Iturriaga, Carla Flores

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pamela ThomsonEscuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile. pamela.thomson@unab.cl.
Rodrigo SantibáñezDepartment of Bioengineering, Center for Microbiome Innovation, University of California San Diego, La Jolla, USA.
Daniel GarridoDepartamento de Ingeniería Química y Bioprocesos, Facultad de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.
María Paz IturriagaEscuela de Medicina Veterinaria, Facultad de Agronomía e Ingeniería Forestal, Facultad de Ciencias Biológicas y Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Carla FloresUnidad Medicina Felina, Clínica Veterinaria Los Avellanos, Santiago, Chile.

Funding

ANID Fondecyt Iniciación #11231174
6 · The paper itself

Abstract

Periodontal disease is a multifactorial condition commonly observed in domestic cats, characterized by inflammation and alveolar bone loss. This study aimed to elucidate the differences in the oral microbiome between healthy cats and those with periodontitis, focusing on microbial community structure and preliminary functionality. An observational case-control study was conducted involving 30 cats, divided equally into healthy and periodontitis groups. Gingival swabs were collected and analyzed using V3_V4 regions of the 16S rRNA sequencing. The results revealed that while the dominant phyla in both groups were Bacteroidota and Bacillota, cats with periodontitis exhibited decreased levels of Ochrobactrum, Odoribacter denticanis, Treponema denticola, Porphyromonas macacae, and Fretibacterium fastidiosum which are the characteristics of the periodontal oral microbiome. Predicted function indicated the enrichment of pathways related to the biosynthesis of fatty acids in periodontal disease, such as ubiquinol and mycolate production. These findings highlight significant microbial and functional shifts associated with feline periodontal disease, providing a basis for potential diagnostic and therapeutic strategies.

Indexed as

BacteriaCat DiseasesMicrobiotaMouthPeriodontal DiseasesPeriodontitisAnimalsCase-Control StudiesCatsFemaleMaleRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.