Evidence map›Paper›PMID 40295325›Full record

ArticleEnvironmental monitoring and assessment2025

Heavy metals in spices from Lancaster, PA: arsenic, cadmium, and lead exposure risks and the need for regulation.

Andrew Huff, Hoi Lam, Anuj Ghimirey, Jay Goldring, Michelle Pimentel, Harriet Okatch

Abstract read
In one paragraph

Article in Environmental monitoring and assessment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrew HuffCollege of Population Health, Thomas Jefferson University, Philadelphia, PA, USA.
Hoi LamTouro College of Osteopathic Medicine, New York, NY, USA.
Anuj GhimireyKornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Jay GoldringSchool of Graduate Studies, Rutgers University, New Brunswick, NJ, USA.
Michelle PimentelCollege of Population Health, Thomas Jefferson University, Philadelphia, PA, USA.
Harriet OkatchCollege of Population Health, Thomas Jefferson University, Philadelphia, PA, USA. harriet.okatch@jefferson.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metal exposure is associated with adverse health effects in children including impaired cognitive functioning. Studies have identified spices as a potential source of heavy metals. However, in Lancaster, PA no such studies have been conducted. Hence the aim of this study was to quantify arsenic (As), cadmium (Cd) and lead (Pb) in spices from Lancaster, PA. Spices were either purchased from stores in Lancaster or obtained as donations from families in Lancaster. As, Cd, and Pb were quantified using inductively coupled plasma-mass spectrometry. The Wilcoxon rank sum test was used to compare the median heavy metal concentrations in store-purchased and home-donated spices. An exposure assessment was conducted to determine the estimated daily intake (EDI) for the metals. As, Cd, and Pb were detected in over 90% of the samples. The As, Cd and Pb median concentrations were 0.048, 0.056 and 0.177 ppm, respectively. 40.5% of the samples exceeded the Pb limit set by the New York State Department of Health; 6.03% and 3.45% of the samples exceeded the As and Cd limits, respectively. Only the As concentration differed significantly (p = 0.001) between the store-purchased (0.055 ppm) and home-donated spices (0.034 ppm). The EDI for As, Cd, and Pb based on the median concentrations was 0.016 ug/day, 0.020 ug/day, and 0.062 ug/day, respectively. The elevated lead content in the spices suggests continuous monitoring of heavy metals in spice samples. Standardized guidelines for maximum permissible limits of heavy metals could improve food safety.

Indexed as

Environmental ExposureFood ContaminationMetals, HeavySpicesArsenicCadmiumDietary ExposureEnvironmental MonitoringHumansLeadRisk AssessmentArsenicCadmiumLeadMetals, HeavyArsenicCadmiumHeavy metalsLeadRegulationSpices

Identifiers

PMID40295325
PMCPMC12037643

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.