Evidence map›Paper›PMID 40295022›Full record

ArticleIn vivo (Athens, Greece)

Spot Scanning Proton Beam Therapy for Surgery-inaccessible Hepatocellular Carcinoma: Preliminary Results.

Yutaka Fujimoto, Sachika Shiraishi, Masashi Yamanaka, Akihiro Yamano, Kazuki Matsumoto, Shintaro Shiba, Toshitaka Tsukiyama, Masahiro Kobayashi, Koichi Tokuuye

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yutaka FujimotoDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Sachika ShiraishiDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan; s-nogi@tokyo-med.ac.jp.
Masashi YamanakaDepartment of Medical Physics, Shonan Kamakura General Hospital, Kamakura, Japan.
Akihiro YamanoDepartment of Medical Physics, Shonan Kamakura General Hospital, Kamakura, Japan.
Kazuki MatsumotoDepartment of Medical Physics, Shonan Kamakura General Hospital, Kamakura, Japan.
Shintaro ShibaDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Toshitaka TsukiyamaInterventional Radiology Center, Shonan Kamakura General Hospital, Kamakura, Japan.
Masahiro KobayashiGastroenterology Medicine Center, Shonan Kamakura General Hospital, Kamakura, Japan.
Koichi TokuuyeDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSpot scanning proton beam therapy (SS-PBT) was employed for the treatment of surgery-inaccessible hepatocellular carcinoma, primarily influenced by respiratory movement. PATIENTS AND

methodsBetween October 2022 and December 2023, 12 patients were enrolled in this study to evaluate the efficacy of SS-PBT. The median follow-up time was 13.1 months.

resultsThe one-year survival, progression-free survival, and local control rates were 79.5%, 57.1%, and 100%, respectively, without grade 2 or higher PBT-related toxicities. The clinical outcomes of these 12 patients appear comparable to data from prospective studies conducted at proton centers across Japan.

conclusionSS-PBT shows promise as a treatment option for surgery-inaccessible hepatocellular carcinoma.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsProton TherapyAdultAgedFemaleHumansMaleMiddle AgedTreatment Outcomehepatocellular carcinomaliver cancerproton beam therapyradiotherapySpot scanning

Identifiers

PMID40295022
PMCPMC12042008

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.