ArticleIn vivo (Athens, Greece)
Controlling Cellular Behavior by Surface Design of Titanium-based Biomaterials.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Effects of sandblasting and acid etching on the surface properties of additively manufactured and machined titanium and their consequences for osteoblast adhesion under different storage conditions.Frontiers in bioengineering and biotechnology · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimTitanium alloys, especially Ti MATERIALS AND
methodsThe adhesion of human osteoblasts to various substrates (either uncoated or coated) was quantified using a lactate dehydrogenase assay and scanning electron microscopy. The surface density of adsorbed human serum albumin was analyzed by the Bradford assay.
resultsApplication of polyelectrolyte multilayer coatings significantly increased the hydrophilicity of titanium substrates without altering their sub-micrometer and micrometer roughness or topography. The coatings rich in reactive amino groups were found to enhance the adsorption of human serum albumin and promote the adhesion of osteoblasts.
conclusionThe chemical composition of the surface, particularly the presence of free primary amino groups, significantly affects cellular behavior in machined, sand-blasted, and additively manufactured titanium materials, while the impact of surface roughness appears secondary. No correlation was observed between surface hydrophilicity and protein adsorption or cell attachment.
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