Trial reportIn vivo (Athens, Greece)
Immersive Virtual Reality for Reducing Intraoperative Pain: A Pilot Randomized Controlled Trial.
Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of Immersive Virtual Reality Interventions on Symptom Management in Patients With Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- The effect of virtual reality on anxiety and pain in patients undergoing totally implantable venous access port: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Efficacy of Virtual Reality-Based Mindfulness Interventions: Systematic Review and Meta-Analysis.JMIR XR and spatial computing · 2026Review
- Exploring the Mental Well-being of Hospitalized Patients: Survey Findings to Inform Future Supportive Interventions.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimIn this study, we aimed to evaluate the effect of virtual reality (VR) therapy on pain, anxiety, and other outcomes in patients with cancer undergoing central venous (CV) port placement. PATIENTS AND
methodsWe conducted a single-center randomized controlled trial with 10 adults with cancer undergoing CV port placement. Participants were randomized into the VR group (n=5), which received VR therapy with the Therapeia VR system (xCura), or the control group (n=5), which underwent conventional procedures. The primary and secondary outcomes included intraoperative pain, intraoperative and postoperative anxiety, blood loss, operative time, sensation of obstruction, and patient and surgeon satisfaction.
resultsNo significant differences were found between the VR and control groups regarding operative time, blood loss, preoperative anxiety, obstruction sensation, or surgeon satisfaction. However, compared with the control group, the VR group showed markedly lower intraoperative pain (
conclusionThe use of immersive VR therapy during CV port placement significantly reduced intraoperative pain and anxiety and enhanced patient satisfaction. These findings indicated that VR therapy may be an effective nonpharmacological adjunct for improving patient experience during invasive procedures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.