Evidence map›Paper›PMID 40294526›Full record

ArticleJournal of neurosurgery. Case lessons2025

Stereo-electroencephalography in the setting of a preexisting deep brain stimulation device: illustrative case.

Stephen Jaffee, Navnika Gupta, Dallas Kramer, Dorian M Kusyk, James Valeriano, Amanda Merkley, Trent Kite, Shaifali Arora, Pulkit Grover, Alexander C Whiting

Abstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stephen JaffeeDepartment of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.
Navnika GuptaDepartment of Neurology, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.ORCID 0000-0001-8044-7539
Dallas KramerDepartment of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.
Dorian M KusykDepartment of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.ORCID 0000-0003-3750-5160
James ValerianoDepartment of Neurology, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.
Amanda MerkleyDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Trent KiteDepartment of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.
Shaifali AroraDepartment of Neurology, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.ORCID 0000-0002-1925-1040
Pulkit GroverDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Alexander C WhitingDepartment of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep brain stimulation (DBS) and responsive neurostimulation are increasingly being used to treat drug-resistant epilepsy (DRE). However, patients who experience partial or limited improvement in seizure control could require additional surgical interventions or refinement of their epilepsy network characterization, including further stereo-electroencephalography (SEEG) investigations. SEEG in the setting of previously implanted hardware demonstrates a myriad of technical challenges. The authors present the first reported demonstration of SEEG electrode implantation with a preexisting DBS device. OBSERVATIONS: The patient was a 36-year-old male with a history of severe DRE with focal impaired awareness seizures beginning at 7 years of age. Despite having a bilateral DBS device for the anterior nucleus of the thalamus, he continued to have 1-2 seizures per day and was offered SEEG. The patient tolerated the surgery well without any morbidity, with a successfully improved definition of his epilepsy network. SEEG allowed the medical team to titrate stimulation settings while following intracranial electrographic response. LESSONS: SEEG in the setting of preexisting DBS can be performed safely without damage to functioning hardware, and the authors obtained characterization and localization of the epilepsy network. Further follow-up will be needed to assess the efficacy outcomes of additional intervention in this patient. https://thejns.org/doi/10.3171/CASE24854.

Indexed as

case reportdeep brain stimulationepilepsystereo-electroencephalography

Identifiers

PMID40294526
PMCPMC12036351

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.