Evidence map›Paper›PMID 40294175›Full record

ArticleStroke2025

High-Dose, High-Intensity Stroke Rehabilitation: Why Aren't We Giving It?

David J Lin, Steven C Cramer, Pierce Boyne, Pooja Khatri, John W Krakauer

Abstract read
In one paragraph

Article in Stroke, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David J LinDepartment of Neurology, Division of Neurocritical Care and Stroke Service, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston (D.J.L.).ORCID 0000-0002-6575-9849
Steven C CramerDepartment of Neurology, University of California, Los Angeles; and California Rehabilitation Hospital (S.C.C.).ORCID 0000-0002-6214-6211
Pierce BoyneDepartment of Rehabilitation, Exercise and Nutrition Sciences, University of Cincinnati College of Allied Health Sciences, OH (P.B.).ORCID 0000-0003-3611-9057
Pooja KhatriDepartment of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, OH (P.K.).ORCID 0000-0002-7344-8266
John W KrakauerDepartment of Neurology, Johns Hopkins University, Baltimore, MD (J.W.K.).

Funding

Validation of Early Prognostic Data for Recovery Outcomes after Stroke for Future, Higher Yield Trials (VERIFY)U01NS120910 · NINDS · YALE UNIVERSITY · PI Steven C. Cramer, Pooja Khatri · 2021 to 2026
$13.5M
NINDS NIH HHS U01 NS120910RRD VA IK2 RX004237
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

activities of daily livingneurological rehabilitationoccupational therapystrokestroke rehabilitation

Identifiers

PMID40294175
PMCPMC12039970

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.