Evidence map›Paper›PMID 40294132›Full record

ArticleMagnetic resonance in medicine2025

Evaluation of diffusion time-dependent changes in radial diffusivity as a surrogate for axon diameter.

Hannah E Alderson, Mark D Does, Elizabeth B Hutchinson, Kevin D Harkins

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah E AldersonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.ORCID https://orcid.org/0009-0009-0408-4831
Mark D DoesDepartment of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Elizabeth B HutchinsonDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona, USA.ORCID https://orcid.org/0000-0002-3374-5469
Kevin D HarkinsDepartment of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA.

Funding

Uncovering the time dependent diffusion coefficient in neural tissue with MRIR01EB031954 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARKINS, KEVIN D · 2021 to 2024
$1.5M
NIBIB NIH HHS 5-R01-EB031954-04NIBIB NIH HHS R01 EB031954
6 · The paper itself

Abstract

purposeTo experimentally evaluate the change in radial diffusivity with diffusion time (

methodsEx vivo ferret spinal cords were imaged via MRI and scanning electron microscopy. Region-of-interest comparisons were made between

resultsA strong linear correlation was found between

conclusionThe value of

Indexed as

AxonsDiffusion Magnetic Resonance ImagingSpinal CordAnimalsFerretsImage Processing, Computer-AssistedMicroscopy, Electron, ScanningMyelin Sheathaxon diameterdiffusion time dependenceOGSE

Identifiers

PMID40294132
PMCPMC12202731

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.