Evidence map›Paper›PMID 40293999›Full record

ArticlePloS one2025

Study protocol for an observational research study with an embedded N-of-1 design: Increasing the availability of goal-oriented cognitive rehabilitation for people living with dementia in Ireland.

Caoimhe Hannigan, Antoine Lemercier, Garret McDermott, Helena Lydon, Sean P Kennelly, Michelle Kelly

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caoimhe HanniganDepartment of Psychology, School of Business, National College of Ireland, Dublin , Ireland.
Antoine LemercierDepartment of Psychology, School of Business, National College of Ireland, Dublin , Ireland.ORCID 0009-0004-4960-8428
Garret McDermottDepartment of Psychology and Regional Specialist Memory Clinic, Tallaght University Hospital, Tallaght, Dublin, Ireland.
Helena LydonSchool of Psychology, University of Galway, Galway, Ireland.ORCID 0000-0002-8202-0843
Sean P KennellyInstitute of Memory and Cognition, Tallaght University Hospital, Dublin, Ireland.
Michelle KellyDepartment of Psychology, School of Business, National College of Ireland, Dublin , Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGoal-Oriented Cognitive Rehabilitation (GREAT-CR) is an evidence-based early intervention for people with mild-moderate dementia that improves goal attainment and functional outcomes. In Ireland, this intervention is not widely available, likely due to resource shortages within memory services. This project aims to pilot and evaluate a new service delivery model for GREAT-CR, and to assess its impact on goal attainment, cognition, and quality of life for people living with dementia.

methodsThis pilot study implements a new service-delivery model where trainee psychologists will offer GREAT-CR within Memory Clinics in Ireland. Sub-study 1 will evaluate the impact of GREAT-CR in this context and sub-study 2 will evaluate the implementation model. Sub-study 1 will employ a quantitative pre-post design with an embedded randomized N-of-1 experimental design. Outcomes will include goal attainment, quality of life, and cognitive function. A subset of three participants will be randomly selected for an N-of-1, single-case experimental design evaluation. The N-of-1 design will include within-case and start-point randomization. Sub-study 2 will include a mixed-methods approach to evaluate the feasibility, acceptability, appropriateness, and potential sustainability of the implementation model at organizational, practitioner, and service-user levels. We will conduct semi-structured interviews with key stakeholders and analyze the data using framework analysis. Quantitative implementation outcomes will be assessed against predefined targets to support qualitative findings. DISCUSSION: The results will inform guidelines for wider service delivery. This project aims to ensure immediate and long-term impacts for participants with early-stage dementia and their carers by increasing opportunities to access evidence-based psychosocial interventions; for trainee psychologists by creating novel placement opportunities; and for service providers by disseminating GREAT-CR implementation recommendations. By addressing current staffing and resource limitations, this model has the potential to enhance the availability of GREAT-CR for dementia patients in Ireland.

Indexed as

DementiaCognitionCognitive TrainingFemaleGoalsHumansIrelandPilot ProjectsQuality of LifeResearch Design

Identifiers

PMID40293999
PMCPMC12036849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.