Evidence map›Paper›PMID 40293933›Full record

ArticleOncology nursing forum2025

Distinct Trajectories of Chemotherapy-Induced Peripheral Neuropathy in Lymphoma Survivors Treated With R-CHOP.

Chih Jung Wu, Ya-Fang Ho, Li-Yuan Bai, Ching Feng Wu, Ting Ting Chen, Ya Jung Wang

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Article in Oncology nursing forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Chih Jung WuChih Jung Wu.
Ya-Fang HoYa-Fang Ho.
Li-Yuan BaiLi-Yuan Bai.
Ching Feng WuChing Feng Wu.
Ting Ting ChenTing Ting Chen.
Ya Jung WangYa Jung Wang.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the trajectories of chemotherapy-induced peripheral neuropathy (CIPN) in lymphoma survivors and assess subdomains of CIPN in this population. SAMPLE &

setting80 newly diagnosed lymphoma survivors treated with R-CHOP were enrolled. METHODS & VARIABLES: CIPN was assessed before chemotherapy (T1), after the first chemotherapy cycle (T2), after the fourth chemotherapy cycle (T3), after the completion of chemotherapy (T4), and 10 weeks post-treatment (T5). CIPN was measured using the Total Neuropathy Score clinical version and the MD Anderson Symptom Inventory.

resultsPatients were categorized into high and low CIPN groups based on CIPN changes over time. The high CIPN group was older and experienced significantly more severe sensory peripheral neuropathy from T1 to T5, with the most severe symptoms observed at T4, followed by T3 and T5. IMPLICATIONS FOR NURSING: Healthcare providers should closely monitor older patients, those with pretreatment peripheral neuropathy symptoms, and those exhibiting pronounced sensory neuropathy during treatment to provide timely and effective symptom management, reducing the impact of CIPN.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsLymphomaPeripheral Nervous System DiseasesSurvivorsAdultAgedAged, 80 and overAntibodies, Monoclonal, Murine-DerivedCyclophosphamideDoxorubicinFemaleHumansMaleMiddle AgedPrednisoneRituximabAntibodies, Monoclonal, Murine-DerivedCyclophosphamideDoxorubicinPrednisoneR-CHOP protocolRituximabVincristinechemotherapy-induced peripheral neuropathylymphomatrajectory modeling

Identifiers

PMID40293933
PMCPMC12056829

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.