ReviewClinical journal of the American Society of Nephrology : CJASN2025
The Cardiovascular-Kidney-Metabolic Health Framework: Implications for Nephrology.
Review in Clinical journal of the American Society of Nephrology : CJASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Renal single-nucleus transcriptomic of a new model of cardiovascular-kidney-metabolic syndrome in aging swine.American journal of physiology. Renal physiology · 2026Article
- A machine learning-derived aging index for risk stratification and mortality prediction in cardiovascular-kidney-metabolic syndrome: A retrospective cohort study.PLoS medicine · 2026Article
- Continuous Glucose Monitoring and Mortality Risk Among U.S. Veterans Receiving Dialysis With Diabetes.Diabetes care · 2026Article
- Intersection of Pediatric Hypertension and Cardiovascular-Kidney-Metabolic Disease.Current hypertension reports · 2026Review
- Metabolic Dysfunction-Associated Steatotic Liver Disease and Kidney Transplant Outcomes.Kidney international reports · 2026Article
- Developmental origins and environmental determinants of cardiovascular-kidney-metabolic syndrome: A pediatric precision prevention perspective.Biomedical journal · 2026Review
- Correlation between the modified cardiometabolic index and the incidence of cardiovascular disease in a population with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study.Scientific reports · 2026Article
- A Tale of Two Syndromes: The Temptation of Expanded Inclusivity in Cardiorenal Medicine.Kidney360 · 2026Article
- National Prevalence, Regional Distribution, and Risk Factors for CKD in Taiwan.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Current Appraisal and Gaps in Knowledge in Cardio-Kidney Metabolic Syndrome Definition.International journal of molecular sciences · 2026Review
- Network dynamics of metabolic disease continuum in older adults: a 7-year longitudinal cohort study in China.BMC geriatrics · 2025Article
- Leptin and Adiponectin as Uremic Adipokines: Associations with Survival in a Prospective Hemodialysis Cohort.Toxins · 2025Article
- The 2025 AHA/ACC hypertension guidelines: implications for cardiovascular and renal risk in patients with diabetes.Cardiovascular diabetology. Endocrinology reports · 2025Article
- Optimising Access to Care for Patients with Heart and Kidney Diseases: A World Heart Federation and International Society of Nephrology White Paper.Global heart · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic risk factors, CKD, and cardiovascular disease are highly prevalent, frequently coexist, and adversely affect lifespan and health span globally. The American Heart Association (AHA) recently defined Cardiovascular-Kidney-Metabolic (CKM) syndrome to highlight the interconnectedness between these conditions, across biological and socioecological domains. The CKM health initiative of the AHA seeks to improve cardiovascular and kidney health at a population level by providing a holistic approach to the management of individuals with CKM syndrome, emphasizing CKM health across the lifespan with priority for primordial/primary prevention, improving short and long-term cardiovascular risk prediction, and presenting an implementation framework for multidisciplinary health care models across diverse health care settings. CKD is a key risk factor, mediator, and therapeutic target to reduce cardiovascular disease burden and is represented across all aspects of the AHA CKM health framework. This review article highlights the major take-aways for nephrologists from the AHA CKM health initiative. It outlines the areas where nephrologists can affect the delivery of holistic CKM care as part of the multidisciplinary team. Finally, it describes a potential future role for nephrology to guide and implement screening and early interventions for kidney disease, to move the needle toward kidney health at a population level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.