Evidence map›Paper›PMID 40293654›Full record

ArticleJournal of cardiovascular translational research2025

LACC1 Enhances Polyamine Immunometabolism in Inflammatory Macrophages to Inhibit Atherosclerosis Progression.

Jingyong Zhang, Yuan Xu, Zonglin Han, Bingqi Liu, Maohua Wang, Lili Bao, Yuxiang He

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The research progress of LACC1.Frontiers in immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingyong ZhangDepartment of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jing five and Wei seven Road, Jinan, 250021, Shandong, China.
Yuan XuDepartment of Traditional Chinese Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Zonglin HanDepartment of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jing five and Wei seven Road, Jinan, 250021, Shandong, China.
Bingqi LiuDepartment of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jing five and Wei seven Road, Jinan, 250021, Shandong, China.
Maohua WangDepartment of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jing five and Wei seven Road, Jinan, 250021, Shandong, China.
Lili BaoDepartment of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jing five and Wei seven Road, Jinan, 250021, Shandong, China.
Yuxiang HeDepartment of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jing five and Wei seven Road, Jinan, 250021, Shandong, China. 16652049907@163.com.ORCID 0009-0008-9356-4011

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the function and potential mechanism of laccase domain-containing 1 (LACC1) on atherosclerosis (AS). ApoE

Indexed as

AortaAortic DiseasesAtherosclerosisInflammationMacrophagesPolyaminesAnimalsDisease Models, AnimalDisease ProgressionInflammation MediatorsLipoproteins, LDLMaleMiceMice, Inbred C57BLMice, Knockout, ApoENitric Oxide Synthase Type IIInflammation MediatorsLipoproteins, LDLNitric Oxide Synthase Type IINos2 protein, mouseoxidized low density lipoproteinPolyaminesAtherosclerosisInflammationInflammatory macrophagesLACC1Polyamine immunometabolism

Identifiers

PMID40293654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.