ArticleMolecular diversity2026
In silico and in vitro analysis of diethyl phthalate as a quorum sensing inhibitor and its antitumor evaluation against MDA-MB-231 cell lines.
Article in Molecular diversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Diethyl phthalate (DEP), a phthalate acid ester present in naturally occurring substances of living forms including flora, fauna, and microbes, particularly those of the Streptomyces genus, functions as an allelochemical, antibiotic, or pesticide to aid donor species in their adaption. In this in silico experiment, DEP was utilized as a quorum sensing inhibitor (QSI) against the quorum sensing (QS) protein of Chromobacterium violaceum and Pseudomonas aeruginosa such as CviR and LasR. We identified that quorum sensing system of both the organisms tested may be blocked due to the utilization of DEP, which contributes to our knowledge of the molecular process underlying QS-regulated behaviors. In vitro testing of the DEP anticancer efficacy over MDA-MB-231 cells, which revealed considerable cytotoxicity with an IC
Indexed as
Identifiers
40293606What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.