Evidence map›Paper›PMID 40293567›Full record

ArticleWorld journal of urology2025

Robotic partial nephrectomy is associated with a lower incidence of urine leakage following nephron-sparing surgery for kidney tumors compared to open and laparoscopic approaches.

Husny Mahmud, Tomer Erlich, Dorit E Zilberman, Barak Rosenzweig, Orith Portnoy, Zohar A Dotan

Abstract readComparative Study
In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Husny MahmudDepartment of Urology, Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel. Husny.mahmud@sheba.health.gov.il.ORCID https://orcid.org/0009-0005-7846-3544
Tomer ErlichDepartment of Urology, Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.
Dorit E ZilbermanDepartment of Urology, Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.
Barak RosenzweigDepartment of Urology, Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.
Orith PortnoyDiagnostic Imaging Department, Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.
Zohar A DotanDepartment of Urology, Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUrine leakage (UL) is a recognized complication after partial nephrectomy (PN). This study aimed to determine the incidence of UL and identify key risk factors, including tumor size and surgical approach, to clarify the impact of robotic-assisted, laparoscopic, and open PN on postoperative outcomes.

methodsA retrospective review of 785 consecutive clinical T1 PN cases (2012-2022) was undertaken. UL was defined as biochemically confirmed uriniferous drain output ≥ 50 mL day-1 persisting ≥ 3 days. The overall incidence of UL was assessed, and multivariable statistical tests evaluated potential predictors of leakage. (19 events; EPV = 3.8; hypothesisgenerating).

resultsOf the 785 patients, 50.7% had RAPN, 33.8% OPN, and 15.5% LPN. The overall incidence of UL was 2.4%. RAPN demonstrated the lowest leakage rate (0.75%), compared with OPN (3.7%) and LPN (4.91%) (p = 0.03), representing a five-fold reduction in UL risk compared to open and laparoscopic approaches. Patients with T1b tumors were significantly more prone to leakage than those with T1a tumors (15.8% vs. 0.99%; multivariable odds ratio (OR) = 18.8, 95% CI = 7.15-49.44; p < 0.0001). Longer operative and ischemia times were also associated with higher leakage risk. All UL cases resolved with conservative or minimally invasive interventions.

conclusionsSurgical approach, operative duration, ischemia time, and tumor size (T1b vs. T1a) emerged as principal predictors of postoperative UL. RAPN conferred a notably lower leakage risk compared to OPN and LPN, underscoring its advantages for nephron-sparing surgery, particularly in complex renal tumors requiring meticulous collecting-system closure.

trial registrationNot applicable (retrospective).

Indexed as

Kidney NeoplasmsLaparoscopyNephrectomyOrgan Sparing TreatmentsPostoperative ComplicationsRobotic Surgical ProceduresAgedFemaleHumansIncidenceMaleMiddle AgedNephronsRetrospective StudiesMinimally invasive urologyPartial nephrectomyRENAL nephrometryRobotic-assisted partial nephrectomyT1b renal tumorsUrine leakage

Identifiers

PMID40293567
PMCPMC12037642

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.