Evidence map›Paper›PMID 40293519›Full record

ArticleAbdominal radiology (New York)2025

Diagnostic performance of apparent diffusion coefficient values in differentiating benign from malignant lesions in prostate PI-RADS v2.1 category 1 "nodules in nodule".

Minghua Sun, Fei Li, Xiaoyan Zhang, Rui Wu, Wenya Liu, Li Xu, Mengjie Wu, Yangang Wang

Abstract read
In one paragraph

Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minghua SunDepartment of Radiology, The Fuyang Hospital Of Anhui Medical University, No. 99, Mount Huangshan Road, Fuhe Modern Industrial Park, Yingzhou District, Fuyang, Anhui Province, 236000, China. aydfyyysmh@163.com.ORCID 0000-0001-9541-1483
Fei LiDepartment of Radiology, The Fuyang Hospital Of Anhui Medical University, No. 99, Mount Huangshan Road, Fuhe Modern Industrial Park, Yingzhou District, Fuyang, Anhui Province, 236000, China.
Xiaoyan ZhangDepartment of Radiology, The Fuyang Hospital Of Anhui Medical University, No. 99, Mount Huangshan Road, Fuhe Modern Industrial Park, Yingzhou District, Fuyang, Anhui Province, 236000, China.
Rui WuDepartment of Radiology, The Fuyang Hospital Of Anhui Medical University, No. 99, Mount Huangshan Road, Fuhe Modern Industrial Park, Yingzhou District, Fuyang, Anhui Province, 236000, China.
Wenya LiuDepartment of Radiology, The Fuyang Hospital Of Anhui Medical University, No. 99, Mount Huangshan Road, Fuhe Modern Industrial Park, Yingzhou District, Fuyang, Anhui Province, 236000, China.
Li XuDepartment of Radiology, The Fuyang Hospital Of Anhui Medical University, No. 99, Mount Huangshan Road, Fuhe Modern Industrial Park, Yingzhou District, Fuyang, Anhui Province, 236000, China.
Mengjie WuDepartment of Pathology, The Fuyang Hospital Of Anhui Medical University, Fuyang, Anhui Province, China.
Yangang WangDepartment of Urology, The Fuyang Hospital Of Anhui Medical University, Fuyang, Anhui Province, China.

Funding

Natural Science Foundation of Anhui Medical University 2022xkj214Natural Science Research Projects in Higher Education Institutions in Anhui Province 2023AH050584
6 · The paper itself

Abstract

objectivesTo explore the associations between the apparent diffusion coefficient (ADC) values of prostate PI-RADS v2.1 category 1 "nodules in nodule" and their pathological characteristics.

methodsWe retrospectively analyzed the prostate images from 226 male patients who underwent biopsy following MRI from January 2019 to December 2024. Two radiologists evaluated the PI-RADS v2.1 categories of identified nodules, measured the ADC values of the prostate nodules in a double-blind manner, and analyzed the associations between these values and the pathological characteristics of the nodules via independent sample t tests or Mann-Whitney U test.

resultsThe ADC values of PI-RADS v2.1 category 1 "nodules in nodule" pathologically confirmed as clinically significant prostate cancer (csPCa) were lower than those of benign prostate hyperplasia (BPH) ((unit in ×10

conclusionIn patients with PI-RADS v2.1 category 1 "nodules in nodule", when the ADC values are less than 0.835 × 10

Indexed as

ProstateProstatic NeoplasmsAgedAged, 80 and overDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingHumansMaleMiddle AgedProstatic HyperplasiaRetrospective StudiesApparent diffusion coefficientNodule in nodulePI-RADS v2.1Prostate biopsyProstate cancer

Identifiers

PMID40293519
PMCPMC12568914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.