Evidence map›Paper›PMID 40293339›Full record

ReviewCurrent opinion in hematology2025

The interplay between physical and mental health and its impact on outcomes for hemopoietic stem cell transplant patients.

Jennifer Martynowicz, Sarah Gutch, Maegan Capitano

Abstract readReview
In one paragraph

Review in Current opinion in hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer MartynowiczDepartment of Psychiatry.
Sarah GutchDepartment of Microbiology and Immunology, Indiana University School of Medicine; Indianapolis, Indiana, USA.
Maegan CapitanoDepartment of Microbiology and Immunology, Indiana University School of Medicine; Indianapolis, Indiana, USA.

Funding

Project-005U54DK106846 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Reuben Kapur, Karen Elizabeth Pollok · 2015 to 2026
$9.7M
NIDDK NIH HHS U54 DK106846
6 · The paper itself

Abstract

purpose of reviewThe incidence of mental health conditions within hematopoietic stem cell transplant (HSCT) patients is high and has profound impacts on quality of life after transplant. Mental health is an underexplored and underutilized outcome in this patient population. RECENT

findingsStandard mental health interventions in this patient population have shown limited results. Multiple factors including acuity of systemic illness, proinflammatory states, heterogeneous patient populations, and use of specific therapeutics could impact results. This presents the opportunity to identify new areas of improvement, such as focusing on leukocyte recovery, exogenous steroid use, and cytokine response to inform new bedside interventions. SUMMARY: Overall, interventions incorporating the biological mechanisms of mental health are underutilized in the HSCT patient population and offer a novel approach to improving morbidity, mortality and quality of life.

Indexed as

Hematopoietic Stem Cell TransplantationMental DisordersMental HealthHumansQuality of LifeTreatment Outcomecorticosteroidscytokinesdepressionhematopoietic stem cell transplantmental health

Identifiers

PMID40293339
PMCPMC12153076

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.