Evidence map›Paper›PMID 40293285›Full record

ReviewmBio2025

Candidalysin biology and activation of host cells.

Léa Lortal, Claire M Lyon, Jakob L Sprague, Johannes Sonnberger, Olivia K A Paulin, Don N Wickramasinghe, Jonathan P Richardson, Bernhard Hube, Julian R Naglik

Abstract readReview
In one paragraph

Review in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Hemolytic Activity of VaginalPathogens (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Léa LortalCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.ORCID 0009-0004-6221-7763
Claire M LyonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.
Jakob L SpragueDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.
Johannes SonnbergerDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.
Olivia K A PaulinCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.
Don N WickramasingheCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.
Jonathan P RichardsonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.ORCID 0000-0001-9638-2725
Bernhard HubeDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Jena, Germany.ORCID 0000-0002-6028-0425
Julian R NaglikCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.ORCID 0000-0002-8072-7917

Funding

Bundesministerium für Bildung und ForschungDeutsche ForschungsgemeinschaftNIH HHS DE022550Wellcome TrustWellcome Trust 214229_Z_18_Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Candida albicansFungal ProteinsHost-Pathogen InteractionsAnimalsCandidiasisEpithelial CellsHumansImmunity, InnateMacrophagesNeutrophilsECE1 protein, Candida albicansFungal ProteinsCandida albicanscandidalysinfungal infectionimmune mechanismstoxins

Identifiers

PMID40293285
PMCPMC12153327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.