Evidence map›Paper›PMID 40293262›Full record

ArticleMicrobiology resource announcements2025

Plasmid sequences and availability of a two-plasmid system for CRISPRi knockdown of

Michelle Chua, Daniel Erickson, James Collins

Abstract read
In one paragraph

Article in Microbiology resource announcements, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle ChuaDepartment of Microbiology & Immunology, University of Louisville, Louisville, Kentucky, USA.
Daniel EricksonDepartment of Microbiology & Immunology, University of Louisville, Louisville, Kentucky, USA.
James CollinsDepartment of Microbiology & Immunology, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0003-2479-5189

Funding

Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Shirin Ghods · 2018 to 2026
$24.4M
NIGMS NIH HHS 5P20GM125504-07NIGMS NIH HHS P20 GM125504
6 · The paper itself

Abstract

A two-plasmid CRISPRi system for

Indexed as

antibiotic-free maintenanceClostridioides difficileCRISPRidCas9

Identifiers

PMID40293262
PMCPMC12160543

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.