ReviewFuture microbiology
Selected honey as a multifaceted antimicrobial agent: review of compounds, mechanisms, and research challenges.
Review in Future microbiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ManagingMolecules (Basel, Switzerland) · 2025Pooled it
- Mechanistic Insights into Honey-Mediated Antibacterial Activity Against Enterobacteriaceae: A Multifaceted Approach Targeting Membrane Integrity, Protein Synthesis, and Quorum Sensing Inhibition.Probiotics and antimicrobial proteins · 2026Article
- Compositional and Safety Profiling of Honeys From Iraqi Kurdistan: A Multi-Indicator Analytical Approach.Journal of food science · 2026Article
- Inhibition of SARS-CoV-2 spike S1-ACE2 binding interaction and downregulation of ACE2 gene expression by Malaysian stingless bee honey and its bioactive compound, stilbamidine (SDC).Molecular biology reports · 2026Article
- Recent Progress on Polyphenols of Malaysian Honey and Their Molecular Mechanism Pathways in Cancer-A Comprehensive Review.International journal of molecular sciences · 2026Review
- Silver nanoparticles as antimicrobials: A comparative analysis of green and traditional chemistry synthesis methods.PloS one · 2026Article
- In Vitro Antimicrobial Activity of Five Turkish Honey Types Against Otitis Externa Pathogens: A Comparative Study.Sisli Etfal Hastanesi tip bulteni · 2026Article
- Multilayer pH-Responsive Hydrogels Fabricated via Two-Step Ionic Crosslinking: Towards Advanced Wound Dressing Materials.Gels (Basel, Switzerland) · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Honey, derived from floral nectar, has been valued for its nutritional and therapeutic properties, with recent studies emphasizing its broad-spectrum antimicrobial potential, especially against antimicrobial resistance (AMR). Honey's antimicrobial activity stems from its unique composition, including high sugar content, low pH, and bioactive compounds like hydrogen peroxide, methylglyoxal (MGO), and phenolic compounds. Distinct honey types, such as Manuka, Sidr, and Tualang, demonstrate varying antimicrobial effects based on their botanical and geographical origins. Manuka honey, rich in MGO, is notably effective against multidrug-resistant pathogens, while Sidr and heather honeys excel in biofilm inhibition and antioxidative properties. Bioactive components, including phenolics, flavonoids, enzymes, and antimicrobial peptides, disrupt microbial membranes, inhibit metabolic pathways, and induce oxidative stress. Advanced analytical techniques like HPLC and GC-MS have identified these compounds, though gaps remain in understanding secondary metabolites and synergistic actions. This review highlights honey's potential as a sustainable antimicrobial resource, emphasizing the need for standardization, clinical validation, and interdisciplinary research. Honey represents a promising solution to AMR and offers opportunities for integration into modern medicine and healthcare strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.