Evidence map›Paper›PMID 40292577›Full record

ArticlePolymers2025

Transforming Agro-Waste Cutin into Sustainable Materials for Biomedical Innovations.

Gianni Pecorini, Martina Tamburriello, Erika Maria Tottoli, Giangiacomo Beretta, Ida Genta, Bice Conti, Rossella Dorati, Rita Nasti

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gianni PecoriniDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0009-0000-4606-6783
Martina TamburrielloDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Erika Maria TottoliDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Giangiacomo BerettaDepartment of Environmental Science and Policy (ESP), Università degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0003-0987-0857
Ida GentaDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5710-0588
Bice ContiDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-0034-2815
Rossella DoratiDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5774-9547
Rita NastiDepartment of Environmental Science and Policy (ESP), Università degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0001-8207-9450

Funding

Fondazione Cariplo in the framework of the 2021 Call "Circular Economy for a Sustainable Future, for the project entitled "Cutin from Tomato-Peel Waste: Green Source for Plurality of Engineered Polymer Products (CutToPro)" 2021-0651
6 · The paper itself

Abstract

Agricultural waste derivatives, particularly tomato cutin, a biopolymer found in the cuticular layer of plants, present a promising alternative for the development of sustainable materials in biomedical applications. Cutin, composed primarily of fatty acids and hydroxy acids, exhibits favorable biodegradability, biocompatibility, and hydrophobic properties, positioning it as a viable candidate for applications such as drug delivery systems, wound healing, and tissue engineering. This study investigates the extraction, characterization, and potential biomedical utilization of 10,16-dihydroxy hexadecenoic acid monomer derived from tomato cutin agro-waste. The cytotoxicity of cutin-based materials was evaluated through in vitro assays, demonstrating minimal toxicity and confirming their suitability for biomedical applications. The extraction process was optimized using various solvents, and the molecular characteristics of the extracted monomer were assessed using techniques such as Gel Permeation Chromatography (GPC), Gas Chromatography-Mass Spectroscopy (GC-MS)

Indexed as

agricultural wastebio-based polymersbiomass valorizationcircular economycutinfatty acidstomato peels

Identifiers

PMID40292577
PMCPMC11945373

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.