ArticleNutrients2025
Evaluation of Inulin and Polyphenol Content and the Cytotoxicity of
Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed.
- Synergistic Interactions Between Inulin-Type Fructans and Plant Polyphenols: Implications for Antioxidant Activity, Bioavailability, and Functional Food Development.Antioxidants (Basel, Switzerland) · 2026Review
- Comparative Analysis of Polysaccharides from Chicory Roots and Aerial Parts Reveals Comparable Cytoprotective Effects Associated with MAPK/NF-κB Signaling.International journal of molecular sciences · 2026Article
- Research progress in plant endophyte-mediated lignocellulosic biomass degradation and valorization: a review.Archives of microbiology · 2026Review
- Medicinal Plants in Food Supplements for Gastrointestinal Disorders: Critical Assessment of Health Claims on Gastric Acid Regulation.Nutrients · 2025Review
- Techno-Functional Properties and Applications of Inulin in Food Systems.Gels (Basel, Switzerland) · 2025Review
- Phytochemical Profile and Analgesic Properties of Chicory Root Extract in the Hot-Plate Test in Mice.International journal of molecular sciences · 2025Article
- Synergistic potential of natural products and exercise: unveiling molecular mechanisms and innovative therapeutic approaches for liver diseases.Frontiers in nutrition · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
background
objectivesThis study aimed to evaluate the cytotoxicity of
methodsFreeze-dried root extracts were prepared using water and three extraction methods: pectinase-assisted, pressure-assisted, and a combination of both. The contents of inulin, total polyphenols, and total caffeic acid derivatives in the extracts were measured by the Layne-Eynon, Folin-Ciocalteu, and UHPLC-PDA methods, respectively. Cytotoxicity of the extracts and inulin was tested in vitro using the L929 cell line, MTT method, and paracetamol as the reference standard.
resultsInulin levels in the extracts ranged from 43.88 to 50.95 g/100 g dry matter (dm), total polyphenols were between 816.7 and 906.4 mg/100 g dm, and total phenolic acids ranged from 11.50 to 187.1 mg/100 dm, with pressure-assisted extraction yielding the highest phytochemical recovery. The cytotoxicity tests showed IC
conclusionsGiven the high content of active compounds and low cytotoxicity, the root extracts of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.