Evidence map›Paper›PMID 40292338›Full record

ArticleCell insight2025

The role of TRPV4 in acute sleep deprivation-induced memory impairment: Mechanisms of calcium dysregulation and synaptic plasticity disruption.

Meimei Guo, Feiyang Zhang, Sha Liu, Yi Zhang, Lesheng Wang, Jian Song, Wei Wei, Xiang Li

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell insight, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Fiber photometry-based analysis of transcranial magneto-acoustic electrical stimulation effects on synaptic plasticity in the hippocampal CA1 region of APP/PS1 mice].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Meimei GuoBrain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, Hubei, China.
Feiyang ZhangBrain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, Hubei, China.
Sha LiuDepartment of General Practice, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, China.
Yi ZhangBrain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, Hubei, China.
Lesheng WangBrain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, Hubei, China.
Jian SongDepartment of Neurosurgery, General Hospital of Central Theater Command, Wuhan 430070, Hubei, China.
Wei WeiBrain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, Hubei, China.
Xiang LiBrain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute sleep deprivation (ASD) impairs memory formation, but the underlying mechanisms remain unclear. In this study, we employed an ASD model combined with fear conditioning to investigate these mechanisms. mRNA sequencing revealed upregulated expression of Transient Receptor Potential Vanilloid 4 (TRPV4), a nonselective Ca

Indexed as

Learning and memoryPostsynaptic density protein 95 (PSD95)Sleep deprivation (SD)Synaptic plasticityTransient receptor potential vanilloid 4 (TRPV4)

Identifiers

PMID40292338
PMCPMC12023795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.