Evidence map›Paper›PMID 40292274›Full record

ArticleJournal of arrhythmia2025

Prediction of difficulty in cryoballoon ablation with a three-dimensional deep learning model using polygonal mesh representation.

Kazutaka Nakasone, Makoto Nishimori, Masakazu Shinohara, Kunihiko Kiuchi, Mitsuru Takami, Kimitake Imamura, Yu Izawa, Toshihiro Nakamura, Yusuke Sonoda, Hiroyuki Takahara and 7 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kazutaka NakasoneDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.ORCID https://orcid.org/0000-0002-0262-9932
Makoto NishimoriDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Masakazu ShinoharaDivision of Molecular Epidemiology Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Kunihiko KiuchiDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Mitsuru TakamiDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.ORCID https://orcid.org/0000-0002-1768-802X
Kimitake ImamuraDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Yu IzawaDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.ORCID https://orcid.org/0000-0002-2688-3468
Toshihiro NakamuraDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.ORCID https://orcid.org/0000-0003-0521-3008
Yusuke SonodaDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Hiroyuki TakaharaDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Kyoko YamamotoDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Yuya SuzukiDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.ORCID https://orcid.org/0000-0002-6790-0914
Kenichi TaniDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Hidehiro IwaiDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Yusuke NakanishiDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Ken-Ichi HirataDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.
Koji FukuzawaDivision of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Hyogo Japan.ORCID https://orcid.org/0000-0003-4276-479X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cryoballoon ablation (CBA) is useful for pulmonary vein (PV) isolation. However, some cases are challenging, requiring multiple applications and/or touch-up ablations. Although several predictors of CBA difficulty have been reported, none have assessed the spatial location and morphology of the left atrium and PVs. This study aimed to develop a three-dimensional (3D) deep learning (DL) model to predict CBA difficulty and compare its accuracy with conventional manual measurement. Methods: A 28-mm cryoballoon (Arctic Front Advance, Medtronic) was used in all cases. CBA difficulty was defined as requiring touch-up ablation and/or more than three applications per PV. We developed a DL model that can learn polygonal meshes and predict CBA difficulty. In the conventional method, predictors included a thinner left lateral ridge, higher left superior PV (LSPV) ovality index, longer LSPV ostium-bifurcation distance, and shorter right inferior PV ostium-bifurcation distance. Results: A total of 189 patients who underwent CBA for drug-resistant atrial fibrillation between January 2015 and January 2022 were included. The DL model was superior to the conventional method in accuracy (0.793 vs. 0.630, Conclusions: We developed a 3D DL model that can detect CBA difficulty using a polygonal mesh representation. By predicting difficult cases in advance, strategies can be developed to increase success rates.

Indexed as

artificial intelligenceatrial fibrillationcomputed tomographycryoballoon ablationdeep learning

Identifiers

PMID40292274
PMCPMC12022427

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.