Evidence map›Paper›PMID 40292256›Full record

ArticleOpen medicine (Warsaw, Poland)2025

Toxic metals and metalloids in collagen supplements of fish and jellyfish origin: Risk assessment for daily intake.

Gaetano Cammilleri, Marina Tortorici, Licia Pantano, Francesco Giuseppe Galluzzo, Andrea Pulvirenti, Maria Drussilla Buscemi, Gianluigi Maria Lo Dico, Andrea Macaluso, Vittorio Calabrese, Ursula M Jacob and 1 more

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gaetano CammilleriExperimental Zooprophylactic Institute of Sicily, Via Gino Marinuzzi 3, 90129 Palermo, Italy.
Marina TortoriciExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
Licia PantanoExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
Francesco Giuseppe GalluzzoExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
Andrea PulvirentiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41121 Modena, Italy.
Maria Drussilla BuscemiExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
Gianluigi Maria Lo DicoExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
Andrea MacalusoExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.
Vittorio CalabreseDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Ursula M JacobHealthcare AG, 8001 Zürich, Switzerland.
Vincenzo FerrantelliExperimental Zooprophylactic Institute of Sicily, 90129 Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: We examined marine collagen supplements derived from fish and jellyfish for the presence of toxic metals and metalloids (Pb, Cd, Cr, Hg, and As). A risk assessment was also carried out by converting the obtained concentrations into average daily doses (ADDs) and comparing them with tolerable daily intakes (TDIs) to evaluate potential health risks associated with long-term consumption. Methods: The levels of Pb, Cd, Cr, and As in marine collagen samples were quantified using inductively coupled plasma mass spectrometry (ICP-MS). Mercury levels were analysed with a direct analyser. The study analysed various brands of marine collagen supplements from fish and jellyfish, ensuring compliance with EU regulatory limits. Results: Arsenic was the most abundant element detected, with mean values of 0.59 ± 0.28 mg/kg, followed by Pb (0.13 ± 0.02 mg/kg). Significant variability was observed between brands. Hg was detectable in only 12% of the samples. Marine collagen samples derived from jellyfish and

Indexed as

contaminantsICP-MSmarine collagentoxicology

Identifiers

PMID40292256
PMCPMC12032979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.