Evidence map›Paper›PMID 40292171›Full record

ArticleJournal of craniovertebral junction & spine

How does cervical and cervicothoracic alignment impact horizontal gaze?

Muñoz Montoya Juan Esteban, Ramachandran Karthik, Kelly Razmeender Singh, Shetty Ajoy Prasad, Shanmuganathan Rajasekaran

Abstract read
In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predictive value of C0-C2 and C1-C2 angles for postoperative lower cervical alignment following posterior atlantoaxial fixation and fusion: a retrospective single-center study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muñoz Montoya Juan EstebanNeurosurgeon, Universidad Militar Nueva Granada, Bogotá, Colombia.
Ramachandran KarthikSenior Registrar, Department of Spine Surgery, Ganga Hospital, Coimbatore, Tamil Nadu, India.
Kelly Razmeender SinghNeurosurgeon, Putrajaya Hospital, Malaysia.
Shetty Ajoy PrasadSenior Spine Consultant, Department of Spine Surgery, Ganga Hospital, Coimbatore, Tamil Nadu, India.
Shanmuganathan RajasekaranHead of the Department, Department of Spine Surgery, Ganga Hospital, Coimbatore, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical sagittal alignment maintains horizontal gaze, supports the axial load of the skull, and has a reciprocal relationship to the cervicothoracic sagittal alignment. Studies are being conducted on different ethnicities, but little literature exists about cervical sagittal alignment and correlation chains in the Indian population. Therefore, we decided to study the impact of cervical and cervicothoracic alignment on horizontal gaze. Methods: This is a retrospective cross-sectional study where an asymptomatic adult population from India was enrolled between 18 and 50 years old. The following parameters were measured on lateral cervical x-ray: McGregor slope (McGS), C0-C2 angle, C1-C2 angle, C2 slope, Cervical Lordosis (CL) C2-C7, C7 slope, sagittal vertical axis C2-C7, thoracic inlet angle, neck tilt and T1 slope (T1S). The results were stratified in upper and lower cervical alignment, cervicothoracic alignment, and horizontal gaze parameters (McGS) using Pearson's correlation coefficient. Results: One hundred and four individuals were included. C7 Slope strongly correlated with T1S (r = 0.675, P = 0.000) and a chain of correlation was found between T1S with CL: C2-C7 (r = --0.602), then C0-C2 angle (r = --0.483) and C1-C2 angle (r = --0.592), finally, the McGS (Horizontal Gaze) (r = -0.709), all with P ≤≤ 0.000. The highest correlation was between the C2 Slope and T1S - CL mismatch (r = -0.946, P = 0.000). Conclusion: In the Indian population, a statistically significant correlation chain was found between the upper and lower cervical alignment parameters, cervicothoracic alignment parameters, and horizontal gaze parameters. T1S and C7 Slope are the foundation for starting this correlation chain between the cervical sagittal alignment and the horizontal gaze. In addition, a very important role of the C2 Slope in the cervical sagittal alignment was observed.

Indexed as

Cervical alignmentcorrelationIndian population

Identifiers

PMID40292171
PMCPMC12029384

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.