Evidence map›Paper›PMID 40292137›Full record

ArticleRadiology case reports2025

Histiocytic sarcoma involving multiple abdominal sites: A rare case with KRAS mutation and response to ICE chemotherapy.

Shahad Khalid Hussein Hussein, Olga Tcacenco

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Histiocytic Sarcoma: A Review and Update.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shahad Khalid Hussein HusseinDepartment of Radiology, Aalborg University Hospital, Aalborg, North Jutland, Denmark.
Olga TcacencoDepartment of Radiology, Aalborg University Hospital, Aalborg, North Jutland, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histiocytic sarcoma (HS) is a rare and aggressive malignant neoplasm from histiocytic cells. This case report describes a 52-year-old male with HS involving multiple abdominal sites, diagnosed through imaging, histopathology, and immunohistochemical analysis, which identified a KRAS mutation. The patient underwent surgical resection followed by 6 cycles of ICE chemotherapy, resulting in significant clinical improvement and reduction of tumor burden. This case highlights the clinical presentation, diagnostic challenges, and potential treatment approach for this rare malignancy.

Indexed as

Histiocytic sarcomaImmunohistochemistryJejunumKRAS mutationPelvic wallPeritoneum

Identifiers

PMID40292137
PMCPMC12018173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.