ArticleMultiple sclerosis journal - experimental, translational and clinical
Diagnostic delay and misdiagnosis of symptoms reported by patients with multiple sclerosis participating in a research registry.
Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Living the Masterclass: Multiple Sclerosis Patient Journeys and the Reality of Participatory Medicine.Journal of participatory medicine · 2026Article
- Application of the 2024 McDonald Criteria: Earlier Diagnosis and Avoiding Misdiagnosis of Multiple Sclerosis in a Global Setting.Neurology · 2026Review
- Patient profiles and disease characteristics of the IMSRN cohort: a multicentre study (2021-2025).The Lancet regional health. Southeast Asia · 2026Article
- Obstructed Hemivagina with Ipsilateral Renal Anomaly: Radiological Diagnosis, Outcome of Surgical Management and Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Antigen-Specific Inverse Vaccination Strategies Using Particle Systems for Multiple Sclerosis.ACS biomaterials science & engineering · 2026Review
- Degenerative Cervical Myelopathy Diagnosis and Its Differentiation from Neurological Mimics, MS and ALS: A Literature Review.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Research cohort data suggest diagnostic delay in multiple sclerosis (MS) has diminished in tandem with MS diagnostic criteria revisions, yet other studies have not replicated this finding. Recent data indicate misdiagnosis of initial symptoms of MS is a frequent contributor to diagnostic delay. Objectives: This survey study assessed diagnostic delay and misdiagnosis in an MS patient registry. Methods: Participants completed the survey study between November 12, 2021, through December 22, 2021. Results: There were 428 participants. Diagnostic delay was a median of 2.0 months (mean of 22.8 months, range: 0-32.9 years); 173/428 (40.4%) reported misdiagnosis of symptoms later attributed to MS, and this was associated with longer diagnostic delay ( Conclusions: Diagnostic delay was prevalent and associated with frequent misdiagnosis of initial symptoms of MS and earlier unevaluated symptoms later attributed to MS. Studies tracing the diagnostic journey of patients with MS are needed to understand and prevent causes of diagnostic delay.
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Registered trials
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