Evidence map›Paper›PMID 40292035›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Assessing fall risk in multiple sclerosis using patient-reported outcomes and wearable gait metrics.

Samantha A Banks, Charles L Howe, Jay Mandrekar, Omid Jahanian, Sean J Pittock, Farwa Ali, Jessica A Sagen, Robert Spence, Kellie A Gossman, Matthew R Baker and 4 more

Abstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Sensors in Multiple Sclerosis.Current neurology and neuroscience reports · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Samantha A BanksDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-5856-1367
Charles L HoweDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.
Jay MandrekarDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.
Omid JahanianDepartment of Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-5379-1462
Sean J PittockDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-8387-6491
Farwa AliDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.
Jessica A Sagen
Robert Spence
Kellie A GossmanCenter for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, MN, USA.
Matthew R BakerDepartment of Neurologic Surgery, Mayo Clinic School of Medicine, Rochester, MN, USA.
Eoin P FlanaganDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-6661-2910
Orhun H KantarciDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.
B Mark KeeganDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-2880-935X
W Oliver TobinDepartment of Neurology, Mayo Clinic School of Medicine, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-8141-2394

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Falls in people with multiple sclerosis (pwMS) lead to morbidity and expense. Objective: Identify clinical metrics associated with falls. Methods: Eighty-six pwMS completed fall surveys, timed 25-foot walk (T25FW), and motion analysis with Clario Opal devices. Logistic regression models were created. Results: Median age was 54.5 years (range 21-73), 62% (53) were female. The cohort included 58% with relapsing (50) and 42% with progressive MS (36). Those who reported falling in the last year were older (median age 58 vs 52.5, Conclusions: Falls in pwMS are more frequent in patients who are older, have higher PDDS, slower walking, and worse balance. Gait aid use and T25FW >10.8 s were strongly associated with falls in the past year.

Indexed as

Biomarkersmultiple sclerosisoutcome measurementquality of liferehabilitationsymptomatic treatment

Identifiers

PMID40292035
PMCPMC12033493

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.