ArticleChemistry of materials : a publication of the American Chemical Society2025
Designing Dynamic Hydrogels: The Interplay of Cross-Linker Length, Valency, and Reaction Kinetics in Hydrazone-Based Networks.
Article in Chemistry of materials : a publication of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine.Advanced healthcare materials · 2026Review
- Organocatalytically-Tuned In Situ Formed Alginate Hydrogel Enables Sustained Therapeutic Release.Chemistry, an Asian journal · 2026Article
- Competitive Inhibition as a Tool to Modulate and Predict Dynamic Hydrogel Mechanics.ACS central science · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Hydrogels designed using dynamic (reversible) chemistry are prominent tools in diverse research areas as they grant access to time-dependent mechanical properties (self-healing and viscoelasticity), which are inaccessible via purely covalent networks. While the relationship between rate and equilibrium constants (RECs) and bulk mechanical properties is increasingly explored, less known is the effect of network topology or cross-linker length on both REC's and mechanical properties in dynamically cross-linked hydrogels. Here, we chose hydrazone formation as a model system for dynamic covalent network formation. Using mono- and bivalent hydrazides with molecular weights of 0.1-20 kg·mol
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