ArticleEuropean physical journal plus2025
Photocontrol of bacterial membrane potential regulates antibiotic persistence in
Article in European physical journal plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Bacterial persistence and resistance to antibiotics pose critical challenges in healthcare and environmental contexts. Recent studies revealing that bacteria possess a dynamic electrical membrane potential open new avenues for influencing bacterial behaviour and drug susceptibility. In this work, we present a novel light-responsive strategy to modulate bacterial antibiotic persistence using Ziapin2, an azobenzene photoswitch previously shown to alter bacterial membrane potential. We selected two broad-spectrum antibiotics with distinct modes of action: Kanamycin, which requires cytosolic uptake to inhibit protein synthesis, and Ampicillin, which targets cell wall polymerization at the cell envelope, to probe the role of membrane potential in antibiotic efficacy. Our findings show that when
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Registered trials
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