Evidence map›Paper›PMID 40291895›Full record

ArticleWorld journal of gastrointestinal surgery2025

Pan-immune-inflammation in colon cancer: A prognostic biomarker and the role of tumor location in personalized care.

Gaya Spolverato, Giulia Capelli, Floriane Noel, Michele Steindler, Andrew Alexander Gumbs

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Beyond the biopsy: the new era of non-invasive staging and biomarkers in colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gaya SpolveratoDepartment of Surgery, University of Padova, Padua 35122, Italy.
Giulia CapelliDepartment of Surgery, ASST Bergamo Est, Bergamo 24068, Lombardy, Italy.
Floriane NoelDepartment of Research, Sibylone, Paris 75002, France.
Michele SteindlerDepartment of Research, Sibylone, Paris 75002, France.
Andrew Alexander GumbsDepartment of Surgery, University of Magdeburg, Magdeburg 39130, Saxony-Anhalt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advances in surgery, chemotherapy, and radiotherapy, the treatment of colorectal cancer (CRC) requires more personalized approaches based on tumor biology and molecular profiling. While some relevant mutations have been associated with differential response to immunotherapy, such as

Indexed as

Colorectal cancerInflammatory biomarkersTargeted therapyTumor location

Identifiers

PMID40291895
PMCPMC12019070

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.