ArticleInternational journal of cardiology. Heart & vasculature2025
Prognostic value of myocardial flow reserve by PET imaging in patients with suspected coronary artery disease: A systematic review and meta-analysis.
Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Exploratory Evaluation of Quantitative Rubidium-82 PET Myocardial Perfusion Parameters: Absolute Blood Flow, Flow Reserve, and Left Ventricular Function in an Arabian Gulf Cohort.Journal of clinical medicine · 2026Article
- Intra-Individual Variability of Myocardial Blood Flow and Flow Reserve Assessed by [Diagnostics (Basel, Switzerland) · 2026Article
- Coronary Flow Reserve in Adults: Pathophysiology, Assessment Modalities, Clinical Applications, and Prognostic Significance.Medicina (Kaunas, Lithuania) · 2026Review
- Characteristics associated with abnormal dynamic flow in patients with severe obesity undergoing PET myocardial perfusion imaging.EJNMMI reports · 2026Article
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Authors and funding
18 authors.
Funding
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Abstract
Purpose: We performed a systematic review and Material and methods: Studies published until December 2024 were identified by database search. We included studies evaluating MFR by PET imaging with data on adjusted hazard ratio (HR) for the occurrence of adverse cardiovascular events. Results: We identified 8 eligible articles including 12.087 patients with a mean follow-up of 2.98 ± 0.69 years. The pooled HR for the occurrence of events was 2.19 (95 % CI 1.80-2.68) and no heterogeneity was observed. The pooled incidence rate ratio (IRR) was 3.26 (95 % CI 2.43-4.37) and the heterogeneity was 37.7 %. At Conclusion: MFR assessed by PET imaging is a valuable noninvasive prognostic indicator in the evaluation of patients with suspected CAD.
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