Evidence map›Paper›PMID 40291816›Full record

ArticleMusic and medicine2025

Diary Analysis of an RCT: Natural Language Analyses of Gamma-Music-Based Intervention.

Benjamin M Kubit, Corinna Parrish, Ziyan Zhao, Psyche Loui

Abstract read
In one paragraph

Article in Music and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin M KubitNortheastern University, Boston, Massachusetts, United States.
Corinna ParrishNortheastern University, Boston, Massachusetts, United States.
Ziyan ZhaoNortheastern University, Boston, Massachusetts, United States.
Psyche LouiNortheastern University, Boston, Massachusetts, United States.

Funding

Gamma-Music Based Intervention for Mild Alzheimer's DiseaseR01AG078376 · NIA · NORTHEASTERN UNIVERSITY · PI Edward W Large, Psyche Loui · 2022 to 2026
$2.7M
SynchronyGamma: A Music-Based Intervention for Alzheimer's and Mild Cognitive ImpairmentR43AG078012 · NIA · OSCILLOSCAPE, LLC · PI LARGE, EDWARD W, LOUI, PSYCHE · 2022 to 2022
$450k
Multimodal Musical Stimulation for Healthy Neurocognitive AgingR21AG075232 · NIA · NORTHEASTERN UNIVERSITY · PI LARGE, EDWARD W, LOUI, PSYCHE · 2022 to 2023
$434k
NIA NIH HHS R01 AG078376NIA NIH HHS R21 AG075232NIA NIH HHS R43 AG078012
6 · The paper itself

Abstract

Recent findings in Alzheimer's Disease research has suggested that light entrainment in the form of gamma-band (40 Hz) stimulation can ameliorate Alzheimer's-associated pathology and improve cognition. Here we report feasibility of a music-based intervention that is coupled with light entrainment in the gamma band, as well as a control intervention that pairs podcast listening with lights tuned to delta but not gamma band frequencies. We compare qualitative data from participant-maintained logbooks (diaries) and researcher notes using Natural Language Processing (NLP) methods, specifically word count and sentiment analysis, and show that while both music-listening and podcast-listening participants were able to complete the interventions, participants in the podcast intervention wrote more words in their logbooks. Results suggest the importance of naturalistic data obtained from diary studies as a snapshot of ongoing interventions.

Indexed as

Alzheimer’s Diseaselightsmusicnatural language processing

Identifiers

PMID40291816
PMCPMC12026446

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.