ArticleAir quality, atmosphere, & health2023
Prenatal Exposure to Ambient Particle Radioactivity and Fetal Growth in Eastern Massachusetts.
Article in Air quality, atmosphere, & health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exposure to radon and ambient particle radioactivity during pregnancy and adverse maternal, fetal and perinatal outcomes: The current literature and potential mechanisms.Environmental research · 2024Pooled it
- Associations Between Gestational Residential Radon Exposure and Term Low Birthweight in Connecticut, USA.Epidemiology (Cambridge, Mass.) · 2024Article
- Associations of solar activity and related exposures with fetal growth.The Science of the total environment · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Background: The radioactive component of particulate matter (PM), particle radioactivity (PR), can continue to emit radiation after inhalation. While PR has been associated with other adverse pregnancy outcomes, no studies have examined the association with fetal growth. Methods: Our retrospective cohort included singleton pregnancies that underwent obstetric ultrasounds at an academic medical center in Massachusetts from 2011 through 2016. PR was represented by particle gross β-activity estimated from an ensemble model and was assigned based on residential zip-code. We considered the cumulative (conception until date of fetal growth measurement) and first 16 weeks of gestation PR exposure windows. Standardized z-scores were constructed for biparietal diameter (BPD), head circumference, femur length (FL), abdominal circumference (AC), and birth weight. We used linear mixed regression models adjusted for PM ≤2.5 μm exposure, maternal sociodemographic factors, meteorological variables, and long-term trends. Results: Among 9,404 pregnancies, an interquartile range increase in cumulative PR exposure was associated with reduced BPD (-0.06 [95% CI: -0.12, -0.01] z-score) and FL (-0.06 [95% CI: -0.12, -0.01] z-score) in scans conducted before 24 weeks' gestation, with increased AC (0.05 [95% CI: 0.01, 0.09]) in scans conducted on or after 24 weeks' gestation, and with lower birth weight (-0.05 [95% CI: -0.11, -0.001] z-score). The first 16 weeks of gestation was not a critical exposure window. Conclusions: Prenatal PR was associated with fetal growth, with associations generally negative before 24 weeks' gestation and positive later in pregnancy. Our findings bring awareness to a novel environmental exposure.
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Registered trials
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