Evidence map›Paper›PMID 40291774›Full record

ArticleOpen life sciences2025

Decreased serum TIMP4 levels in patients with rheumatoid arthritis.

Jinyu Chen, Yanyan Fan, Shengyu Cui, Haiping Zhang, Ziliang Yu, Yali Jiang, Xiaogang Zhou

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinyu ChenDepartment of Orthopedics, The Second Affiliated Hospital of Nantong University, No. 666, Shengli Road, Nantong, 226001, China.
Yanyan FanDepartment of Orthopedics, Ili & Jiangsu Joint Institute of Health, Ili 835100, China.
Shengyu CuiDepartment of Orthopedics, The Second Affiliated Hospital of Nantong University, No. 666, Shengli Road, Nantong, 226001, China.
Haiping ZhangDepartment of Orthopedics, The Second Affiliated Hospital of Nantong University, No. 666, Shengli Road, Nantong, 226001, China.
Ziliang YuDepartment of Orthopedics, The Second Affiliated Hospital of Nantong University, No. 666, Shengli Road, Nantong, 226001, China.
Yali JiangDepartment of Orthopedics, Ili & Jiangsu Joint Institute of Health, Ili 835100, China.
Xiaogang ZhouDepartment of Orthopedics, The Second Affiliated Hospital of Nantong University, No. 666, Shengli Road, Nantong, 226001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study was designed to explore the clinical significance of serum tissue inhibitor of metalloproteinase 4 (TIMP4) levels in rheumatoid arthritis (RA). The GSE1919 chip was analyzed, differentially expressed genes (DEGs) were identified, and gene ontology as well as Kyoto Encyclopedia of Genes and Genomes analyses of the identified DEGs were conducted. Patients with RA (

Indexed as

diagnosisinterleukinrheumatoid arthritisTIMP4

Identifiers

PMID40291774
PMCPMC12032977

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.