Evidence map›Paper›PMID 40291773›Full record

ArticleOpen life sciences2025

p-Cymene inhibits pro-fibrotic and inflammatory mediators to prevent hepatic dysfunction.

Muhammad Atif, Muhammad Nasir Hayat Malik, Tariq G Alsahli, Muhammad Ali, Waqas Younis, Khalid Saad Alharbi, Sami I Alzare, Bader Alsuwayt, Tahir Maqbool, Irfan Anjum and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Muhammad AtifFaculty of Pharmacy, The University of Lahore, Lahore 54000, Pakistan.
Muhammad Nasir Hayat MalikFaculty of Pharmacy, The University of Lahore, Lahore 54000, Pakistan.
Tariq G AlsahliDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf 72341, Saudi Arabia.
Muhammad AliFaculty of Pharmacy, The University of Lahore, Lahore 54000, Pakistan.
Waqas YounisFaculty of Pharmacy, The University of Lahore, Lahore 54000, Pakistan.
Khalid Saad AlharbiDepartment of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al-Qassim, 51452, Saudi Arabia.
Sami I AlzareDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf 72341, Saudi Arabia.
Bader AlsuwaytDepartment of Pharmacy Practice, College of Pharmacy, University of Hafr Al-Batin, Hafr Al-Batin 31991, Saudi Arabia.
Tahir MaqboolInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan.
Irfan AnjumShifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad 44000, Pakistan.
Shah JahanDepartment of Immunology, University of Health Sciences, Lahore 54000, Pakistan.
Abdullah R AlanziDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Gideon F B SolreDepartment of Chemistry, Thomas J. R. Faulkner College of Science and Technology, University of Liberia, Monrovia, Montserrado, Liberia.ORCID https://orcid.org/0000-0002-2861-0674
Hafiz Muhammad BilalFaculty of Pharmacy, The University of Lahore, Lahore 54000, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the hepatoprotective potential of p-cymene (p-CYM) against two models of liver damage: ethanol (EtOH)-induced hepatocellular injury and diethylnitrosamine-carbon tetrachloride (DEN-CCl

Indexed as

DEN- CCl4hepatoprotectiveHepG2liver fibrosisp-cymeneTGF-β1

Identifiers

PMID40291773
PMCPMC12032992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.