Evidence map›Paper›PMID 40291743›Full record

ArticlebioRxiv : the preprint server for biology2025

Structural and Functional Studies of Rabbit SAMD9 Reveal a Distinct tRNase Module That Underlies the Antiviral Activity.

Juhi Chaturvedi, Fushun Zhang, Chen Zhang, Sonal Badhe, Yan Xiang, Junpeng Deng

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Juhi ChaturvediDepartment of Biochemistry and Molecular biology, Oklahoma State University, 246 Noble Research Center, Stillwater, OK 74078, USA.
Fushun ZhangDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Chen ZhangDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Sonal BadheDepartment of Biochemistry and Molecular biology, Oklahoma State University, 246 Noble Research Center, Stillwater, OK 74078, USA.
Yan XiangDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.ORCID 0000-0002-7633-1629
Junpeng DengDepartment of Biochemistry and Molecular biology, Oklahoma State University, 246 Noble Research Center, Stillwater, OK 74078, USA.ORCID 0000-0002-5254-7775

Funding

Novel Translational Control Mechanisms in Host Range Restriction of PoxvirusR01AI151638 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI YAN XIANG · 2020 to 2026
$3.4M
NIAID NIH HHS R01 AI151638
6 · The paper itself

Abstract

Human SAMD9 and SAMD9L (collectively SAMD9/9L) are large cytoplasmic proteins with antiviral and antiproliferative activities, recently shown to regulate protein synthesis by specifically cleaving phenylalanine tRNA (tRNA

Identifiers

PMID40291743
PMCPMC12027330

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.