Effects of Inhaled Dexamethasone/Ciprofloxacin on Acute Subglottic Stenosis in a Rabbit Model.

I-Chun Kuo, Catherine K Hart, Isabelle M Gengler, Alessandro de Alarcón

Abstract read

In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

I-Chun KuoDepartment of Otolaryngology-Head & Neck Surgery Chang Gung Memorial Hospital Taoyuan Taiwan.ORCID https://orcid.org/0000-0002-1617-2507

Catherine K HartDivision of Pediatric Otolaryngology-Head and Neck Surgery Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.ORCID https://orcid.org/0000-0003-0670-9937

Isabelle M GenglerDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine University of Cincinnati Cincinnati Ohio USA.

Alessandro de AlarcónDivision of Pediatric Otolaryngology-Head and Neck Surgery Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.ORCID https://orcid.org/0000-0003-4792-4676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Subglottic stenosis (SGS) is a challenging complication post-airway interventions. Effective preventive strategies lack sufficient evidence. This study investigated the preventive effect of inhalation therapy with dexamethasone/ciprofloxacin on acute SGS in a rabbit model. Methods: Twenty New Zealand White rabbits underwent subglottic injury via endoscopy and received inhalation therapy twice daily starting on the injury day. Group 1 ( Results: Histological analysis revealed median cricoid lumen measurements of 20.01 ± 1.42 mm Conclusion: Short-term dexamethasone/ciprofloxacin inhalation does not prevent acute SGS. No improvements in cricoid lumen diameter were found. Extended survival correlated with shorter cricoid lumen, suggesting SGS progression is time dependent. Level of Evidence: NA.

Indexed as

animal modeldexamethasone/ciprofloxacininhalationsubglottic stenosis

Identifiers

PMID40291573

DOI10.1002/lio2.70119

PMCPMC12023402

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.