ArticleCommunications physics2025
Fast high-resolution lifetime image reconstruction for positron lifetime tomography.
Article in Communications physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- First ex-vivo positronium imaging of tissues with modular J-PET scanner usingZeitschrift fur medizinische Physik · 2026Article
- First positronium lifetime imaging usingScientific reports · 2026Article
- High-Resolution Positronium Lifetime Tomography at Clinical Activity Levels on the PennPET Explorer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT.Frontiers in nuclear medicine · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the ortho-positronium formed prior to the annihilation, the lifetime of a positron is sensitive to the tissue microenvironment and can potentially provide valuable information for monitoring disease progression and treatment response. However, the lifetime of positrons before annihilation has long been overlooked in current positron emission tomography (PET). Here we develop a positron lifetime image reconstruction method called SIMPLE (Statistical IMage reconstruction of Positron Lifetime via time-wEighting) and demonstrate its performance using a real scan on a time-of-flight PET scanner. The SIMPLE method achieves high-resolution positron lifetime imaging of extended heterogeneous tissue illuminated by a
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