Evidence map›Paper›PMID 40291435›Full record

ArticlePulmonary circulation2025

A Subgroup Reanalysis of the Efficacy of Bufei Huoxue Capsules in Patients With "Long-Covid-19".

Chi Hou, Yue Xing, Yuqin Chen, Tingping Wang, Jingjing Qi, Xiaoqing Jia, Xiansheng Zeng, Jianling Bai, Wenju Lu, Yu Deng and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Chi HouState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Yue XingState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.ORCID 0000-0002-2243-9693
Yuqin ChenState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.ORCID https://orcid.org/0000-0002-7011-7250
Tingping WangDepartment of Out-Patient and Emergency Wuhan Institute for Tuberculosis Control, Wuhan Pulmonary Hospital Wuhan China.
Jingjing QiDepartment of Respiratory and Critical Care Medicine Xiangzhou District People's Hospital Xiangyang China.
Xiaoqing JiaDepartment of Respiratory Third Hospital of Baotou City Baotou China.
Xiansheng ZengDepartment of Respiratory and Critical Care Medicine Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science Xiangyang Hubei China.
Jianling BaiDepartment of Biostatistics, School of Public Health Nanjing Medical University Nanjing China.
Wenju LuState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Yu DengDepartment of Radiology The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Bihua ZhongState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.ORCID 0000-0001-5498-0858
Yongxia LeiDepartment of Radiology The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Yilin ChenState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Zhan LianDepartment of Out-Patient and Emergency Wuhan Institute for Tuberculosis Control, Wuhan Pulmonary Hospital Wuhan China.
Haohao ZhouDepartment of Respiratory and Critical Care Medicine Xiangzhou District People's Hospital Xiangyang China.
Junping YanDepartment of Respiratory Third Hospital of Baotou City Baotou China.
Xuejiao YangDepartment of Respiratory and Critical Care Medicine Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science Xiangyang Hubei China.
Hao YuDepartment of Biostatistics, School of Public Health Nanjing Medical University Nanjing China.ORCID 0000-0001-6715-6673
Jiawei ZhouDepartment of Biostatistics, School of Public Health Nanjing Medical University Nanjing China.
Lixia QiuHangzhou YITU Healthcare Technology Co. Ltd. Hangzhou China.
Yunliang ZhaiDepartment of R&D Guangdong Leiyunshang Pharmaceutical Co. Ltd. Yunfu China.
Wanli GengDepartment of R&D Guangdong Leiyunshang Pharmaceutical Co. Ltd. Yunfu China.
Nanshan ZhongState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.ORCID 0000-0003-2274-1427
Chunli LiuState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Jian WangState Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bufei huoxue capsules (BFHX), manufactured products of traditional Chinese medicine, have demonstrated anti-inflammatory properties and efficacy against chronic pulmonary diseases and COVID-19. This study was designed to further determine the clinical efficacy of BFHX in diverse patient subgroups during the convalescent phase of COVID-19, extending upon previously reported findings from a multicenter randomized controlled trial. Patients who had clinically recovered from COVID-19 were blindly assigned to BFHX or placebo groups. All enrolled patients underwent chest computed tomography (CT) imaging, 6-min walking distance (6MWD) test, and fatigue assessment inventory (FAI) at monthly follow-up for 3 months. A post hoc subgroup reanalysis was performed on subgroups of sex, age, severity of acute illness, and positive/negative IgG antibody against S antigen variants. A total of 129 patients were enrolled in BFHX (

Indexed as

bufei huoxue capsulespost‐acute COVID‐19 syndromesubgroup reanalysissymptom recoverytraditional Chinese medicine

Identifiers

PMID40291435
PMCPMC12034259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.