Evidence map›Paper›PMID 40291334›Full record

ArticleCureus2025

Central Nervous System Involvement in Splenic Marginal Zone Lymphoma.

Kabeer Ali, Jennifer Miatech, Falguni Patel, Abhinav Karan, Walter Jr Quan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kabeer AliInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Jennifer MiatechHematology and Oncology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Falguni PatelInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Abhinav KaranInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Walter Jr QuanHematology and Oncology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marginal zone B-cell lymphoma (MZL) represents a heterogeneous group of indolent non-Hodgkin lymphomas (NHL) originating from the marginal zone of B cells in lymphoid tissues. Typically, MZL is classified as nodal, extranodal, and MZL with splenic involvement. Central nervous system (CNS) involvement is rare, whether it presents as a primary dural lymphoma or as a consequence of secondary CNS involvement. CNS involvement of MZL presents with non-specific symptoms such as headaches, focal neurological deficits, cognitive impairment, and seizures in the setting of mass effect. It is essential to consider new CNS infiltration as a possibility in patients with hematological malignancies who exhibit new neurologic symptoms. Herein, we present a case of a patient with a ventriculoperitoneal shunt and recently diagnosed with splenic MZL who presented with status epilepticus and was subsequently diagnosed with secondary CNS involvement, highlighting its associated diagnostic and therapeutic challenges.

Indexed as

cns lymphomageneralized seizureintrathecal infusionintrathecal therapymarginal zone lymphoma (mzl)marginal zone lymphoma mzlrituximab therapysplenic marginal zone lymphomaventriculo-peritoneal shunt surgeryventriculoperitoneal (vp) shunt

Identifiers

PMID40291334
PMCPMC12031390

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.