Evidence map›Paper›PMID 40291300›Full record

ArticleCureus2025

Chronic Myeloid Leukemia in a Young Adult.

Kalan Patel, Jawhar Syed, Ashwin Jagadish, Venkata Vedantam, Daniel Daugherty

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kalan PatelInternal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, USA.
Jawhar SyedInternal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, USA.
Ashwin JagadishInternal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, USA.
Venkata VedantamInternal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, USA.
Daniel DaughertyInternal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic myeloid leukemia (CML) is a hematological malignancy commonly affecting older adults. This unusual case involves a 29-year-old male who presented with significant leukocytosis and thrombocytosis. He was later found to possess a mutation resulting in the fusion of the Abelson murine leukemia (ABL1) gene with the breakpoint cluster gene, resulting in the BCR-ABL1 translocation gene. This is also known as the Philadelphia chromosome and predisposed him to the malignancy. This atypical presentation highlights the importance of considering CML in younger patients, broadening differential diagnoses. Understanding such rare but possible occurrences provides insight into patient-centered treatment plans and potentially curative therapies specific to adolescents and young adults.

Indexed as

adolescent and young adultsbcr-abl1chronic myeloid leukemia (cml)fluorescence in situ hybridization (fish)myeloproliferative

Identifiers

PMID40291300
PMCPMC12023010

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.