ArticleCureus2025
Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Synergistic Therapeutic Effects of Chitosan and Royal Jelly.Polymers · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to investigate the efficacy of a commercially available manuka honey-based face serum that includes royal jelly and bee venom on various ingredients frequently associated with skin health benefits over an eight-week period. MATERIALS AND
methodsForty female participants aged 40-55 with self-reported skin health concerns were recruited. Participants used the serum twice daily and completed questionnaires during Weeks 2, 4, and 8. Photos of the face were analyzed for dermatological skin grading and Optic Elite facial analysis at Week 8.
resultsThere were significant improvements in fine lines, wrinkles, dark spots, hyperpigmentation, dryness, and overall skin health beginning at Week 2, with sustained enhancements observed until Week 8. Dermatologist skin grading results were mixed, with 20 (60.6%) of participants demonstrating improvements in skin brightness, but lower percentages of participants showed improvement in overall skin health, fine lines/wrinkles, roughness, pigmentation, and redness/erythema. Optic Elite analysis showed improvements in several skin health scores, providing further evidence for the serum's effects on skin health. Participants self-reported high satisfaction with the effectiveness of the serum.
conclusionsThese findings suggest that the face serum may be an effective skincare product for improving skin health and mitigating signs of aging.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.