ArticleCureus2025
Diagnostic Dilemma: Metastatic Breast Adenocarcinoma Presenting With a Cholestatic Liver Injury Without Radiological Findings of Liver Metastases.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholestasis refers to a reduction in bile flow caused by either impaired secretion or obstruction. Cancers may manifest with cholestasis due to metastasis (either obstruction or infiltration), paraneoplastic syndromes, or as a side effect of treatment (chemotherapy, immunotherapy, or radiation). Various imaging techniques, including ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) scans, are typically used to assess the obstruction, its location, and the underlying cause. We are presenting a complex and challenging case of metastatic breast cancer in the liver that presented as cholestatic liver injury without corresponding radiological findings. We aim to highlight the importance of considering liver metastasis as a differential diagnosis, even in the absence of supporting radiological evidence.
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Registered trials
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